503179-70-2 Usage
Uses
Used in Pharmaceutical Research and Development:
3-Trifluoromethoxybenzenesulfonamide is used as a key intermediate in the synthesis of novel medicinal compounds for various therapeutic applications. Its unique chemical structure allows for the development of drugs with improved efficacy and selectivity.
Used as an Enzyme Inhibitor:
3-Trifluoromethoxybenzenesulfonamide is utilized as an enzyme inhibitor in drug discovery, targeting specific enzymes involved in disease pathways. Its ability to inhibit these enzymes can lead to the development of treatments for various diseases and conditions.
Used in Drug Discovery and Development:
3-Trifluoromethoxybenzenesulfonamide is employed as a potential therapeutic agent in drug discovery and development. Its interaction with various biological targets makes it a promising candidate for the treatment of different diseases, including those that are currently challenging to address with existing medications.
Used in Chemical Synthesis:
3-Trifluoromethoxybenzenesulfonamide is used as a building block in the chemical synthesis of various compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity contribute to the development of new and innovative products across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 503179-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,1,7 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 503179-70:
(8*5)+(7*0)+(6*3)+(5*1)+(4*7)+(3*9)+(2*7)+(1*0)=132
132 % 10 = 2
So 503179-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F3NO3S/c8-7(9,10)14-5-2-1-3-6(4-5)15(11,12)13/h1-4H,(H2,11,12,13)
503179-70-2Relevant academic research and scientific papers
N-acyl sulfamide FBPase inhibitor, preparation method thereof, drug composition and application
-
Paragraph 2512; 2514; 2515, (2017/09/08)
The invention discloses an N-acryl sulfamide FBPase inhibitor of a novel structure, and a preparation method thereof, a drug composition and an application, and particularly relates to an N-acryl sulfamide FBPase inhibitor shown in the formula I, a salt thereof for medicine, a preparation method, a composition comprising one or more compounds, an application of the compound in preparing the FBPase inhibitor or a drug for treating FBPase-related diseases, and an application in preparing a drug for preventing and/or treating diabetes. The formula is shown in the description.
Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase
Patil, Vikas,Kale, Manoj,Raichurkar, Anandkumar,Bhaskar, Brahatheeswaran,Prahlad, Dwarakanath,Balganesh, Meenakshi,Nandan, Santosh,Shahul Hameed
supporting information, p. 2222 - 2225 (2014/05/06)
Novel triazolopyrimidine acylsulfonamides class of antimycobacterial agents, which are mycobacterial acetohydroxyacid synthase (AHAS) inhibitors were designed by hybridization of known AHAS inhibitors such as sulfonyl urea and triazolopyrimidine sulfonamides. This Letter describes the synthesis and SAR studies of this class of molecules by variation of two parts of the molecule, the phenyl and triazolopyrimidine rings. SAR study describes optimisation of enzyme potency, whole cell potency and evidence of mechanism of action.
