503271-70-3Relevant academic research and scientific papers
Evaluation of a series of bicyclic CXCR2 antagonists
Walters, Iain,Austin, Caroline,Austin, Rupert,Bonnert, Roger,Cage, Peter,Christie, Mark,Ebden, Mark,Gardiner, Stuart,Grahames, Caroline,Hill, Steven,Hunt, Fraser,Jewell, Robert,Lewis, Shirley,Martin, Iain,Nicholls, David,Robinson, David
, p. 798 - 803 (2008/09/18)
The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement of the aminothiazole ring with a 2-thiazolone alternat
PYRIMIDYL SULPHONE AMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS
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, (2008/06/13)
A compound of formula (I), pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof for the treatment of asthma, allergic rhinitis, COPD, inflammatory bowel disease, irritable bowel syndrome, osteoarthritis, osteoporosis, rheumatoid
