503271-69-0

Upstream product

• 1004-40-6 4-aminothiouracil 
• 113211-94-2 2,3-difluorobenzyl bromide 

Downstream Products

• 676345-24-7 4-amino-2-[[(2,3-difluorophenyl)methyl]thio]-1,6-dihydro-6-oxo-5-pyrimidinyl ester thiocyanic acid 
• 676345-23-6 5-[[(2,3-difluorophenyl)methyl]thio]-7-[[2-hydroxy-1-(hydroxymethyl)-1-methylethyl]amino]-thiazolo[4,5-d]pyrimidin-2(3H)-one, monosodium salt 
• 676345-25-8 2-[[2-chloro-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-2-methyl-1,3-propanediol 
• 676345-22-5 5-[[(2,3-difluorophenyl)methyl]thio]-7-[[2-hydroxy-1-(hydroxymethyl)-1-methylethyl]amino]-thiazolo[4,5-d]pyrimidin-2(3H)-one 
• 855476-58-3 7-amino-5-[[(2,3-difluorophenyl)methyl]thio][1,3]oxathiolo[5,4-d]-pyrimidin-2-one 
• 503271-70-3 6-chloro-2-[(2,3-difluorobenzyl)thio]pyrimidin-4-amine 
• 676345-24-7 C₁₂H₈F₂N₄OS₂ 
• 676345-69-0 5-[((2,3-difluorophenyl)methyl)thio]-7-{[(1S,2S)-2-hydroxy-1-(hydroxymethyl)propyl]amino}thiazolo[4,5-d]pyrimidin-2(3H)-one 
• 676345-71-4 2-({2-chloro-5-[((2,3-difluorophenyl)methyl)thio]thiazolo[4,5-d]pyrimidin-7-yl}amino)-(2S,3S)-butane-1,3-diol 
• 259100-41-9 2-amino-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-7(6H)-one 
• 259103-43-0 7-chloro-5-[(2,3-difluorobenzyl)sulfanyl][1,3]thiazolo[4,5-d]pyrimidin-2-amine 
• 654072-55-6 N-((1R)-2-{[tert-butyl(dimethyl)silyl]oxy}-1-methylethyl)-2-[(2,3-difluorobenzyl)thio]pyrimidine-4,6-diamine 
• 503271-71-4 (2R)-2-({6-amino-2-[(2,3-difIuorobenzyl)thio]pyrimidin-4-yl}amino)propan-1-ol 

Relevant academic research and scientific papers

Evaluation of a series of bicyclic CXCR2 antagonists

The CXCR2 SAR of a series of bicyclic antagonists such as the 2-aminothiazolo[4,5-d]pyrimidine 3b was investigated by systematic variation of the fused pyrimidine-based heterocyclic cores. Replacement of the aminothiazole ring with a 2-thiazolone alternat

NOVEL COMPOUND

A compound of formula (I) and pharmaceutically acceptable salts or solvates thereof for use in therapy.

PYRIMIDYL SULPHONE AMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

A compound of formula (I), pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof for the treatment of asthma, allergic rhinitis, COPD, inflammatory bowel disease, irritable bowel syndrome, osteoarthritis, osteoporosis, rheumatoid

NOVEL COMPOUND

A compound of formula (I) and pharmaceutically acceptable salts or solvates thereof for use in therapy.