503274-68-8Relevant academic research and scientific papers
Annulation of the Cyclohexane Ring by Tandem Free Radical Alkylation of a Nonactivated δ-carbon Atom-Intramolecular Carbanion Cycloalkylation
Petrovic, Goran,Cekovic, Zivorad
, p. 3769 - 3772 (2000)
formula presented Annulation of the cyclohexane ring by a combination of free radical and ionic reactions sequences was achieved. Free radical alkylation of the remote nonactivated δ-carbon atom involves addition of δ-carbon radicals, generated by 1,5-hydrogen transfer in alkoxy radical intermediates, to radicophilic olefins, while the polar sequence involves enolate anions as intermediates which undergo a cycloalkylation reaction. Thus, the cyclohexane ring was constructed using diverse acyclic and cyclic structures as precursors of alkoxy radicals.
INSECT PHEROMONES AND THEIR ANALOGUES XL. SYNTHESIS OF DODEC-3Z-EN-11RS-OLIDE (FERRULACTONE II - A RACEMIC ANALOGUE OF A COMPONENT OF THE AGGREGATION PHEROMONE OF Cryptolestes ferrugineus
Odinokov, V. N.,Ishmuratov, G. Yu.,Botsman, L. P.,Vakhidov, R. R.,Ladenkova, I. M.,et al.
, p. 369 - 374 (2007/10/02)
A new route, based on the partial ozonolysis of ω-acetyl derivatives of alk-1-en-4-ynes, is proposed for the synthesis of 11RS-hydroxydodec-3Z-enoic acid, the cyclization of which gives dodec-3Z-en-11RS-olide (ferrulactone II) - a racemic analogue of one of the macrolide components of the aggregation pheromone of the rust-red grain beetle.
