25368-54-1

Basic information

• Product Name: 8-Hydroxy-2-octanone
• Synonyms: 8-Hydroxy-2-octanone
• CAS NO: 25368-54-1
• Molecular Formula: C₈H₁₆O₂
• Molecular Weight: 144.21144
• Mol File: 25368-54-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 138-139 °C(Press: 12 Torr)
• Appearance: /
• Density: 0.948 g/cm3
• PKA: 15.18±0.10(Predicted)
• CAS DataBase Reference: 8-Hydroxy-2-octanone(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Hydroxy-2-octanone(25368-54-1)
• EPA Substance Registry System: 8-Hydroxy-2-octanone(25368-54-1)

Safety Data

• Hazardous Substances Data: 25368-54-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 5785, 1990 DOI: 10.1016/S0040-4039(00)97959-0

Upstream product

• 36219-80-4 7-oxo-octanal 

Downstream Products

• 16209-10-2 7-Hydroxy-octanoic acid benzyl ester 
• 16209-13-5 7-(3.5-Dimethoxy-phenylacetoxy)-octansaeure-benzylester 
• 77128-20-2 benzyl 7-oxooctanoate 
• 823-76-7 Cyclohexyl methyl ketone 
• 334-20-3 (E)-9-oxo-dec-2-enoic acid 
• 503274-68-8 Toluene-4-sulfonic acid 7-oxo-octyl ester 
• 14112-98-2 7-oxooctanoic acid 
• 3664-70-8 trans-1-(2-methylcyclopentyl)ethanone 
• 13175-44-5 oct-7-en-1-ol 

Relevant articles and documents

Synthesis of a multifunctional pheromone of the honeybee Apis mellifera via condensation of 7-oxooctanal with malonic acid

Condensation of 7-oxooctanal with malonic acid in a Doebner reaction produces 9-oxo-2E-decenoic acid (42% yield) and a comparable amount of products from Tishchenko disproportionation of the starting aldehyde (7-oxooctyl-7- oxooctanoate) and re-esterification by acetic acid (7-oxooct-1-ylacetate and 7-oxooctanoic acid).