503310-83-6Relevant academic research and scientific papers
Towards a DNA-like duplex without hydrogen-bonded base pairs
Mathis, Gerald,Hunziker, Juerg
, p. 3203 - 3205 (2002)
The inverse quadrupolar moments of the phenyl and pentafluorophenyl residues in the non-hydrogen-bonded, artificial base pair shown here promotes strong intramolecular stacking interactions in oligonucleotide duplexes. The greater the number of natural ba
Towards a DNA-like duplex without hydrogen bonds
Mathis, Gerald,Schuetz, Rolf,Hunziker, Juerg
, p. 1183 - 1185 (2007/10/03)
The inverse quadrupolar moments of the phenyl and pentafluorophenyl residues in the base pair P-F5 promotes strong intramolecular stacking interactions in DNA duplexes. The more natural base pairs are replaced by this novel pair the higher the thermodynamic stability of the resulting duplex if they are arranged in an alternating fashion.
