503315-79-5Relevant academic research and scientific papers
Novel coumarin fluorescent dyes: Synthesis, structural characterization and recognition behavior towards Cu(II) and Ni(II)
Li, Hongqi,Cai, Li,Li, Jinxing,Hu, Yixin,Zhou, Pingping,Zhang, Jiming
, p. 309 - 316 (2011)
A series of novel coumarin dyes (3-12) were designed and synthesized. The structures of the dyes were characterized by IR, 1H NMR, 13C NMR, 19F NMR, MS and single crystal X-ray diffraction. 3-(2-Benzoylhydrazonotrifluoroethyl)-7-(N,N-diethylamino)coumarin (11) could recognize Cu2+ and Ni2+ selectively in aqueous solution. Upon addition of Cu2+ or Ni2+ to 11 a blue shift or a bathochromatic shift of the absorption band was observed while the emission band blue-shifted with decrease in the fluorescence intensity. Upon addition of Cu2+ the color of the solution of 11 changed from orange to red. The results showed that 11 could be used as an optical chemosensor of Cu 2+ and Ni2+.
Microwave-assisted TsOH/SiO2-catalyzed one-pot synthesis of novel fluoro-substituted coumarin hydrazones under solvent-free conditions
Yang, Guo-Yu,Yang, Jing-Tian,Wang, Cai-Xia,Fan, Su-Fang,Xie, Pu-Hui,Xu, Cui-Lian
, p. 1 - 8 (2014)
Sixteen novel fluoro-substituted coumarin hydrazones were synthesized from a series of ethyl 2-hydroxy-2-(trifluoromethyl)-2H-chromene-3-carboxylates with supported acid catalyst under microwave-assisted one-pot and solvent free conditions. The structures
Synthesis of 1-(β-coumarinyl)-1-(β-indolyl)trifluoroethanols through regioselective Friedel-Crafts alkylation of indoles with β-(trifluoroacetyl)coumarins catalyzed by Sc(OTf)3
Liu, Xiaobiao,Liu, Ying,Pan, Zhenliang,Shi, Lijun,Wang, Caixia,Wu, Lulu,Xu, Cuilian,Yang, Guoyu,Yu, Qicheng,Yuan, Xinxin
, p. 13929 - 13935 (2020)
A highly efficient Friedel-Crafts alkylation of indole derivatives with β-(trifluoroacetyl)coumarins using Sc(OTf)3 as a catalyst has been developed, which gives regioselective 1,2-adducts to afford 1-(β-coumarinyl)-1-(β-indolyl)trifluoroethanols. A series of tertiary trifluoroethanols containing different indole and coumarin groups were synthesized in moderate to excellent yields (up to 95%) in the presence of 5 mol% catalyst in a short time (only 2 minutes at least). A mechanism of the reaction, in which the trace amount of water plays the role of proton transfer in catalyzing circulation was proposed and confirmed.
Fluorine-containing coumarin thiazole compound and synthetic method thereof
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, (2018/03/01)
The invention discloses a fluorine-containing coumarin thiazole compound and synthetic method thereof. The synthetic method includes the steps: (1) dissolving a trifluoroacetyl coumarin compound, a thiosemicarbazide compound and an acid catalyst in absolute ethyl alcohol to obtain non-substituted thiosemicarbazone solution after reaction; (2) adding 2-bromoacetophenone into the non-substituted thiosemicarbazone solution in the step (1), taking the absolute ethyl alcohol as solvents, and drying mixture at the indoor temperature to obtain the fluorine-containing coumarin thiazole compound. The synthesized coumarin thiosemicarbazide thiazole compound is a star compound and has active unit structures such as coumarin, trifluoromethyl, Schiff base and thiazole, and the compound has a large pi-pi conjugated system and is expected to become a bioactive substance with high activity or an optical active substance with high fluorescence performance.
LATENT ACIDS AND THEIR USE
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, (2016/09/22)
Compounds of the formula (I) and (IA) wherein X is -O(CO)-; R1 is C1-C12haloalkyl or C6-C10haloaryl; R2 is located in position 7 of the coumarinyl ring and is OR8; R2a, R2b and R2C independently of each other are hydrogen; R3 is C1-C8haloalkyl or C1-C8haloalkyl; R4 is hydrogen; and R8 is C1-C6alkyI; are suitable as photosensitive acid donors in the preparation of photoresist compositions such as used for example in the preparation of spacers, insulating layers, interlayer dielectric films, insulation layers, planarization layers, protecting layers, overcoat layers, banks for electroluminescence displays and liquid crystal displays (LCD).
The first synthesis of 4-unsubstituted 3-(trifluoroacetyl)coumarins by the knoevenagel condensation of salicylaldehydes with ethyl trifluoroacetoacetate followed by chromene-coumarin recyclization
Chizhov, Dmitrii L.,Sosnovskikh, Vyacheslav Ya.,Pryadeina, Marina V.,Burgart, Yanina V.,Saloutin, Victor I.,Charushin, Valery N.
, p. 281 - 285 (2008/12/21)
A series of ethyl 6-substituted 2-hydroxy-2-(trifluoromethyl)-2H-chromene- 3-carboxylates was obtained in good yields via the Knoevenagel condensation of salicylaldehydes with ethyl trifluoroacetoacetate in the presence of piperidinium acetate. The subsequent recyclization of these chromenes proceeds smoothly in refluxing chlorobenzene in the presence of p-toluenesulfonic acid affording previously unknown 3-(trifluoroacetyl)coumarins in moderate to good yields. Georg Thieme Verlag Stuttgart.
