50337-10-5Relevant academic research and scientific papers
Influence des groupes tert-butyle, trimethylsilyle et trimethylgermyle sur la stereochimie de reactions d'addition en serie cyclohexenique. IV. Reduction, par des hydrures complexes, de cyclohexanones β ou γ substituees
Richer, Jean-Claude,Poirier, Marc-Andre,Maroni, Yvette,Manuel, Georges
, p. 1303 - 1306 (2007/10/02)
The synthesis of 5,5-dimethyl-2-tert-butyl- (1a), trimethylsilyl-2 (1b), and -2-trimethylgermyl- (1c) cyclohexanones is described as well as those of 2,2-dimethyl-5-tert-butyl- (2a), 5-trimethylsilyl- (2b), and -5-trimethylgermyl- (2c) cyclohexanones.The stereochemistry of the reduction of these ketones by different hydrides is examined.This latter reaction competes with the cleavage reaction of the C-M bond in the case of β-substituted ketones (M=Si, Ge).
