503416-71-5

Upstream product

• 186581-53-3 diazomethane 
• 59727-98-9 3-[3,4-di(benzyloxy)phenyl]-2-{[(tert-butoxy)carbonyl]amino}propanoic acid 
• 59-92-7 levodopa 
• 100-39-0 benzyl bromide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1421-65-4 L-dopa methyl ester hydrochloride 
• 125228-11-7 3-(3,4-bis-benzyloxyphenyl)-2-tert-(butoxycarbonylamino)propionic acid methyl ester 
• 37169-36-1 methyl (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dihydroxyphenyl)propanoate 

Downstream Products

• 503416-72-6 (S)-methyl N-(tert-butyloxycarbonyl)-β³-homo-3,4-bis(benzyloxy)phenylalanine carboxylate 
• 503416-73-7 (S)-methyl N-(tert-butyloxycarbonyl)-β³-homo-3,4-bis(hydroxy)phenylalanine carboxylate 
• 849743-69-7 (S)-3-Amino-4-(3,4-bis-benzyloxy-phenyl)-butyric acid methyl ester 

Relevant academic research and scientific papers

Synthesis of [18-C-6]-β3-(L)-DOPA, first β-amino acid with a crown-ether receptor side-chain

Terminally protected Boc-β3-(L)-DOPA-OMe has been synthesized from (L)-DOPA by the Arndt-Eistert homologation procedure. Then, a first crown-ether derivative, Boc-[18-C-6]-β3-(L)-DOPA-OMe, has been obtained by bis-O-alkylation of the

Synthesis of terminally protected (S)-β3-H-DOPA by Arndt-Eistert homologation: An approach to crowned β-peptides

Terminally protected Boc-(S)-β3-H-DOPA-OMe has been synthesized from l-DOPA by the Arndt-Eistert homologation procedure. During the synthesis, the side-chain catechol group was temporarily protected by benzylation. The absence of racemization w