50343-12-9

Upstream product

• 6341-99-7 (4-chloro-2-methylphenyl)acetate 
• 86297-37-2 5-chloro-2-methylphenyl acetate 
• 50317-52-7 2-hydroxy-5-chloro-3-hydroxymethylacetophenone 
• 1570-64-5 2-methyl-4-chlorophenol 

Downstream Products

• 119682-34-7 3,6-dibenzyl-10-chloro-8-methyl-1,4,7-trioxa-benz[de]anthracene-2,5-dione 
• 101606-76-2 6-chloro-4,8-dimethyl-2-oxo-2H-chromene-3-carboxylic acid-(2,4-dichloro-phenyl ester) 
• 53346-75-1 4-Chlor-2-aethyl-6-methylphenol 
• 111391-47-0 (E)-3-(4-Benzyloxy-phenyl)-1-(5-chloro-2-hydroxy-3-methyl-phenyl)-propenone 
• 85128-43-4 4-Chloro-2-(1-imidazol-1-yl-vinyl)-6-methyl-phenol 
• 111391-90-3 6-Chloro-2-(4-hydroxy-phenyl)-3-methoxy-8-methyl-chromen-4-one 
• 111391-60-7 2-(4-Benzyloxy-phenyl)-6-chloro-3-hydroxy-8-methyl-chromen-4-one 
• 132020-79-2 2-(4-Benzyloxy-phenyl)-6-chloro-3-methoxy-8-methyl-chromen-4-one 
• 1343513-55-2 C₁₆H₁₂ClNO₅ 
• 1343513-56-3 C₁₆H₁₂Cl₂O₃ 
• 344866-58-6 C₁₆H₁₂Cl₂O₃ 
• 1343513-59-6 C₁₆H₉BrCl₂O₂ 
• 1343513-33-6 6-chloro-8-methyl-2-(4-nitrophenyl)-4H-chromen-4-one 
• 88953-03-1 6-chloro-2-(4-chlorophenyl)-8-methyl-4H-chromen-4-one 

Relevant academic research and scientific papers

Synthesis and evaluation of a radioiodinated 4,6-diaryl-3-cyano-2-pyridinone derivative as a survivin targeting SPECT probe for tumor imaging

Survivin is overexpressed in most of the cancerous tissues but not in terminally differentiated normal tissues, making it an attractive target for diagnosis and therapy of various types of cancers. In this study, we aimed to develop 4,6-diaryl-3-cyano-2-p

Iridium-Catalyzed C(sp3)?H Addition of Methyl Ethers across Intramolecular Carbon–Carbon Double Bonds Giving 2,3-Dihydrobenzofurans

Intramolecular addition of an O-methyl C(sp3)?H bond across a carbon-carbon double bond occurs in the iridium-catalyzed reaction of methyl 2-(propen-2-yl)phenyl ethers. The Ir/(S)-DTBM-SEGPHOS catalyst promotes the reaction efficiently in toluene at 110–135 °C to afford 3,3-dimethyl-2,3-dihydrobenzofurans. Enantioselective C(sp3)?H addition is achieved in the reaction of methyl 2-(1-siloxyethenyl)phenyl ethers, affording enantioenriched 3-hydroxy-2,3-dihydrobenzofuran derivatives with up to 96% ee. (Figure presented.).

Investigation on the substitution effects of the flavonoids as potent anticancer agents: A structure-activity relationships study

Three series of flavonoid analogues substituted with different aminomethyl substitutions at C-6, C-7, and C-8 were designed and synthesized for the structure-activity relationship studies as potent anticancer agents. The prepared analogues were evaluated for their in vitro inhibitory activity against the growth of the hepatic cancer cell lines HepG2 and SMMC-7721. Structure-activity relationships indicated that not only the compounds with amino methyl groups were more active than those without the groups in the same series but also the compounds substituted by aminomethyl groups at position C-8 were more active than those at positions C-6 and C-7.