50351-72-9 Usage
Uses
Used in Organic Synthesis:
2-(Benzylamino)nicotinonitrile is used as an intermediate in organic synthesis for the creation of a variety of chemical compounds. Its presence in the synthesis process is crucial due to its ability to facilitate the formation of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(Benzylamino)nicotinonitrile is utilized as a key component in the research and development of new drugs. Its potential as a building block allows for the modification and enhancement of existing pharmaceuticals, leading to the discovery of novel therapeutic agents.
Used in Medicinal Chemistry:
2-(Benzylamino)nicotinonitrile plays a significant role in medicinal chemistry, where it is employed for the design and synthesis of biologically active compounds. Its structural features make it an attractive candidate for the development of molecules with potential therapeutic applications.
Used in Drug Discovery:
2-(BENZYLAMINO)NICOTINONITRILE is also used in drug discovery processes, where its unique properties are leveraged to identify and optimize new drug candidates. The benzylamine group in 2-(Benzylamino)nicotinonitrile provides a versatile platform for the exploration of new chemical entities with potential medicinal value.
Check Digit Verification of cas no
The CAS Registry Mumber 50351-72-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,5 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50351-72:
(7*5)+(6*0)+(5*3)+(4*5)+(3*1)+(2*7)+(1*2)=89
89 % 10 = 9
So 50351-72-9 is a valid CAS Registry Number.
50351-72-9Relevant academic research and scientific papers
2-Aminopyridines via reaction of pyridine N-oxides and activated isocyanides
Vamos, Mitchell,Cosford, Nicholas D. P.
, p. 2274 - 2280 (2014/04/03)
A practical and efficient method for the synthesis of substituted 2-aminopyridines from pyridine N-oxides is reported. Yields of purified, isolated products of up to 84% are observed for the one-pot, two-step process. The reaction involves an in situ depr
AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE
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Page/Page column 202, (2010/02/14)
A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R 5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
Substituted 2-aminonicotinonitriles
Troschutz,Dennstedt
, p. 85 - 89 (2007/10/02)
Aminolysis of the cyanoketene-O,N-acetal 1 Z/E with the amines 2a,b leads to the E-configurated cyanoketeneaminals 3a,b. Compounds 3a,b are reacted with 1,3-biselectrophiles 4, 6a,b, 9 HCl, 12, 13, 15a,b, 17, and 19 to yield the N2-substituted 2-aminonicotinonitriles 5, 7, 8, 10, 11, 14, 16, and 20. Reaction of some 2-aminonicotinonitriles with an α-phenylethyl substituent in position 2 (14b, 16a, 8a, 20b, 5 and 8b) with PPA leads to the primary 2-aminonicotinonitriles 21a-f.
