503537-68-6Relevant articles and documents
Isopentenyldiphosphate Isomerase. Machanism of Active-Site-Directed Irreversible Inhibition by 3-(Fluoromethyl)-3-butenyl Diphosphate
Poulter, C. Dale,Muehlbacher, Manfred,Davis, Darrell R.
, p. 3740 - 3742 (1989)
Isopentenyldiphosphate:dimethylallyldiphosphate isomerase catalyzes an antarafacial proton migration by an electrophilic addition-elimination mechanism.Incubation of yeast isomerase with 3-(fluoromethyl)-3-butenyl diphosphate (3) led to rapid inacti