503543-74-6Relevant academic research and scientific papers
Synthesis and antibacterial activity of benzothiazole and benzoxazole-appended substituted 1,2,3-triazoles
Chahal, Manisha,Kaushik, C. P.
, (2020/10/29)
Abstract: A series of benzothiazole and benzoxazole linked 1,4-disubstituted 1,2,3-triazoles was synthesized through copper(I) catalyzed azide-alkyne cycloaddition reaction. FTIR, 1H, 13C-NMR and HRMS techniques were used to examine the structure of synthesized derivatives. Further, these triazole derivatives were screened for in vitro antibacterial activities against two Gram-positive bacteria S. aureus, B. subtilis; two Gram-negative bacteria E. coli and K. pneumoniae by serial dilution technique, reflecting moderate to good activity. Compound 7s exhibited promising antibacterial activity among all the synthesized triazoles. Graphic abstract: [Figure not available: see fulltext.]
Synthesis and evaluation of 2-tosylamino and 2-tosyliminopyrimidine derivatives as inhibitors of some leukocyte functions
Fernandez-Ferri, Patricia,Ubeda, Amalia,Guillen, Isabel,Lasri, Jamal,Gonzalez-Rosende, M. Eugenia,Akssira, Mohamed,Sepulveda-Arques, Jose
, p. 289 - 296 (2007/10/03)
We have studied the potential anti-inflammatory effects of 20 2-tosylamino and 2-tosyliminopyrimidine new derivatives in human neutrophils. We have evaluated their interference with some leukocyte functions and 5-lipoxygenase activity. All the compounds r
