50361-97-2

Basic information

• Product Name: 2-Piperidinone, 3-benzoyl-1-methyl-
• CAS NO: 50361-97-2
• Molecular Formula: C13H15NO2
• Molecular Weight: 217.268
• Mol File: 50361-97-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Piperidinone, 3-benzoyl-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinone, 3-benzoyl-1-methyl-(50361-97-2)
• EPA Substance Registry System: 2-Piperidinone, 3-benzoyl-1-methyl-(50361-97-2)

Safety Data

• Hazardous Substances Data: 50361-97-2(Hazardous Substances Data)

Upstream product

• 931-20-4 1-methylpiperidin-2-one 
• 98-88-4 benzoyl chloride 
• 1934-92-5 N-methyl-N-phenyl-benzamide 

Downstream Products

• 116461-08-6 N-allyl-3-oxo-3-phenyl propionic amide 

Relevant articles and documents

Nickel-Catalyzed Claisen Condensation Reaction between Two Different Amides

A nickel-catalyzed Claisen condensation reaction between two amides, where one possesses an α-proton, for the synthesis of β-ketoamides was developed. Ni(glyme)Cl2 and terpyridine serve as the active catalysts in the presence of Mn and LiCl. N,N-Methylphenyl and N,N-diphenyl benzamide derivatives react with cyclic and noncyclic amides to give their corresponding β-ketoamides in moderate to good yields. In addition, a DFT calculation suggests that reductive elimination is the rate-determining step.