5038-12-0

Basic information

• Product Name: 4-(2-hydroxy-ethyl)-morpholin-2-one
• Synonyms: 4-(2-hydroxy-ethyl)-morpholin-2-one
• CAS NO: 5038-12-0
• Molecular Weight: 145.158
• Mol File: 5038-12-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2-hydroxy-ethyl)-morpholin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-hydroxy-ethyl)-morpholin-2-one(5038-12-0)
• EPA Substance Registry System: 4-(2-hydroxy-ethyl)-morpholin-2-one(5038-12-0)

Safety Data

• Hazardous Substances Data: 5038-12-0(Hazardous Substances Data)

Upstream product

• 150-25-4 N,N-bis-(2-hydroxyethyl)glycine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 150-25-4 N,N-bis-(2-hydroxyethyl)glycine 
• 105-59-9 N-Methyldiethanolamine 

Relevant articles and documents

Facile hydrolysis and formation of amide bonds by N-hydroxyethylation of α-amino acids

The C-terminal amides of α-amino acids are readily hydrolyzed at 25°and pH 7 when the N-terminus is N-hydroxyethylated, with one or two hydroxyethyl The reaction proceeds via cyclization to a morpholinolactone (2) which is rapidly hydrolyzed by water. In the presence of equimolar amounts of amines or amino acid derivatives, 2 reacts in H2O without condensing agents to form a new peptide bond.