50392-57-9Relevant academic research and scientific papers
The typical crystal structures of a few representative α-aryl-α-hydroxyphosphonates
Rádai, Zita,Kiss, Nóra Zsuzsa,Czugler, Mátyás,Karaghiosoff, Konstantin,Keglevich, Gy?rgy
, p. 283 - 293 (2019/02/19)
The crystal structures of seven α-aryl-α-hydroxyphosphonates synthesized by the Pudovik reaction of substituted benzaldehydes and dialkyl phosphites, namely dimethyl [(hydroxy) (phenyl) methyl] phosphonate, C9H13O4P, dimet
The preparation of dimethyl α-hydroxyphosphonates and the chemical shift non-equivalence of their diastereotopic methyl ester groups
Hudson, Harry R.,Yusuf, Ramon O.,Matthews, Ray W.
experimental part, p. 1527 - 1540 (2009/05/30)
Dimethyl α-hydroxyalkyl-, α-hydroxybenzyl-, α-hydroxyfurfuryl-, and α-hydroxy-α-thienylmethyl-phosphonates have been prepared in good yield by the alumina-catalyzed reaction of dimethyl phosphite with the corresponding alkanals, aryl aldehydes (or aryl methyl ketones), furfuraldehyde, and 2- or 3-thiophenecarboxaldehyde, respectively, thus confirming the general utility of this synthetic procedure. The 1H and 13C nmr spectra of the products exhibit characteristic chemical shift non-equivalence of the diastereotopic methyl ester groups, for which a tentative order of non-equivalence is reported and discussed. Copyright Taylor & Francis Group, LLC.
REGIOSPECIFICALLY SUBSTITUTED DEOXIBENZOINS BY HORNER CONDENSATION OF AROMATIC ALDEHYDES WITH O-PROTECTED α-ARYL-α-HYDROXYMETHANEPHOSPHONATES
Napolitano, Elio,Ramacciotti, Antonella
, p. 19 - 22 (2007/10/02)
Dimethyl-α-aryl-α-hydroxymethanephosphonates, prepared by addition of dimethyl phosphite to the appropriate aromatic aldehyde, Ar-CHO, have been protected at oxygen by reaction with 3,4-dihydro-2H-pyran catalyzed by p-toluenesulphonic acid and condensed w
