50413-53-1 Usage
Uses
Used in Pharmaceutical Industry:
Methyl 2-amino-4-isopropoxy-5-methoxybenzoate is used as a reactant in the preparation and structure-activity relationship of anilinocyanoquinolines and anilinoquinazolines. These compounds are known to be inhibitors of Src tyrosine kinase, a protein that plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. By inhibiting Src tyrosine kinase, these compounds have the potential to treat various diseases, such as cancer, autoimmune disorders, and inflammatory conditions.
In the development of new drugs, Methyl 2-amino-4-isopropoxy-5-methoxybenzoate serves as a versatile building block that can be modified and combined with other chemical entities to create novel and effective pharmaceutical agents. Its unique structure and reactivity make it an essential component in the synthesis of anilinocyanoquinolines and anilinoquinazolines, which have shown promising inhibitory effects on Src tyrosine kinase. This, in turn, opens up new avenues for the treatment of various diseases and conditions that are associated with the dysregulation of this important protein.
Check Digit Verification of cas no
The CAS Registry Mumber 50413-53-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,4,1 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 50413-53:
(7*5)+(6*0)+(5*4)+(4*1)+(3*3)+(2*5)+(1*3)=81
81 % 10 = 1
So 50413-53-1 is a valid CAS Registry Number.
50413-53-1Relevant academic research and scientific papers
Inhibitors of Src tyrosine kinase: The preparation and structure-activity relationship of 4-anilino-3-cyanoquinolines and 4-anilinoquinazolines
Wang, Yanong D.,Miller, Karen,Boschelli, Diane H.,Ye, Fei,Wu, Biqi,Floyd,Powell, Dennis W.,Wissner, Allan,Weber, Jennifer M.,Boschelli, Frank
, p. 2477 - 2480 (2007/10/03)
Src is a nonreceptor tyrosine kinase involved in signaling pathways that control proliferation, migration, and angiogenesis. Increased Src expression and activity are associated with an increase in tumor malignancy and poor prognosis. Several quinolines and quinazolines were identified as potent and selective inhibitors of Src kinase activity. (C) 2000 Elsevier Science Ltd.
