3535-27-1

Usage

Uses

Used in Pharmaceutical Industry:
4-ISOPROPOXY-3-METHOXYBENZOIC ACID METHYL ESTER is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs and organic compounds.
Used in Flavor and Fragrance Industry:
4-ISOPROPOXY-3-METHOXYBENZOIC ACID METHYL ESTER is used as a flavoring agent and fragrance ingredient, leveraging its properties to enhance the sensory experience of various products.
It is important to handle and store 4-ISOPROPOXY-3-METHOXYBENZOIC ACID METHYL ESTER with care, as it may pose health and safety risks if not properly managed.

Upstream product

• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 75-26-3 isopropyl bromide 
• 75-30-9 2-iodo-propane 

Downstream Products

• 948553-02-4 4-isopropoxy-5-methoxy-2-nitro-benzoic acid methyl ester 
• 3535-33-9 4-isopropyloxy-3-methoxybenzoic acid 
• 214470-68-5 7-(3-chloro-propoxy)-4-chloro-6-methoxy-quinoline-3-carbonitrile 
• 319492-96-1 7-isopropyloxy-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile 
• 741276-43-7 7-isopropyloxy-6-methoxy-4-chloroquinoline-3-carbonitrile 
• 263149-10-6 4-chloro-7-hydroxy-6-methoxyquinolin-3-carbonitrile 
• 50413-53-1 methyl 2-amino-4-isopropoxy-5-methoxybenzoate 

Relevant academic research and scientific papers

VU6010608, a Novel mGlu7 NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides

Herein, we report the structure-activity relationships within a series of mGlu7 NAMs based on an N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamide core with excellent CNS penetration (Kp 1.9-5.8 and Kp,uu 0.4-1.4). Analogues in this series displayed steep SAR. Of these, VU6010608 (11a) emerged with robust efficacy in blocking high frequency stimulated long-term potentiation in electrophysiology studies.

ANTIVIRAL COMPOUNDS

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

Inhibitors of Src tyrosine kinase: The preparation and structure-activity relationship of 4-anilino-3-cyanoquinolines and 4-anilinoquinazolines

Src is a nonreceptor tyrosine kinase involved in signaling pathways that control proliferation, migration, and angiogenesis. Increased Src expression and activity are associated with an increase in tumor malignancy and poor prognosis. Several quinolines and quinazolines were identified as potent and selective inhibitors of Src kinase activity. (C) 2000 Elsevier Science Ltd.