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1-(4-BROMO-PHENYL)-1H-PYRROLE is an organic compound that belongs to the pyrrole and phenyl groups. It is characterized by its molecular structure, which contains a bromine atom attached to the fourth carbon atom in the phenylethene chain and a pyrrole ring. Pyrroles are heterocyclic aromatic organic compounds, made of five atoms including one nitrogen atom. The presence of the bromine atom makes it useful for various chemical reactions and industrial applications, as bromine compounds are typically used as intermediates in organic synthesis.

5044-39-3

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5044-39-3 Usage

Uses

Used in Research and Industrial Processes:
1-(4-BROMO-PHENYL)-1H-PYRROLE is used as a chemical intermediate for various organic synthesis processes. Its unique molecular structure, which includes a bromine atom and a pyrrole ring, makes it a valuable compound for researchers and industry professionals to explore its potential applications and reactions.
Used in Chemical Synthesis:
1-(4-BROMO-PHENYL)-1H-PYRROLE is used as a building block in the synthesis of more complex organic compounds. Its bromine atom can be easily replaced or modified in chemical reactions, allowing for the creation of new compounds with different properties and applications.
Used in Pharmaceutical Industry:
1-(4-BROMO-PHENYL)-1H-PYRROLE is used as a starting material or intermediate in the development of pharmaceutical compounds. Its unique structure and reactivity make it a promising candidate for the synthesis of new drugs with potential therapeutic effects.
Used in Material Science:
1-(4-BROMO-PHENYL)-1H-PYRROLE can be used in the development of new materials with specific properties, such as conductivity, stability, or reactivity. Its molecular structure and bromine atom can be utilized to create materials with tailored characteristics for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 5044-39-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,4 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5044-39:
(6*5)+(5*0)+(4*4)+(3*4)+(2*3)+(1*9)=73
73 % 10 = 3
So 5044-39-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H8BrN/c11-9-3-5-10(6-4-9)12-7-1-2-8-12/h1-8H

5044-39-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-Bromophenyl)pyrrole

1.2 Other means of identification

Product number -
Other names 1-(4-bromophenyl)pyrrole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5044-39-3 SDS

5044-39-3Relevant academic research and scientific papers

New Pyrrole-Based Organic Dyes for Dye-Sensitized Solar Cells: Convenient Syntheses and High Efficiency

Li, Qianqian,Lu, Lanlan,Zhong, Cheng,Huang, Jing,Huang, Qing,Shi, Jie,Jin, Xianbo,Peng, Tianyou,Qin, Jingui,Li, Zhen

, p. 9664 - 9668 (2009)

Harvesting the sunshine : Two new pyrrole-containing organic dyes were rationally designed and easily prepared. Thanks to the special electronic properties of pyrrole moieties and the introduction of the non-coplanar aromatic rings through a single bond (

A novel electrochromic polymer containing triphenylamine derivative and pyrrole

Ouyang, Mi,Wang, Genghao,Zhang, Cheng

, p. 4645 - 4649 (2011)

A novel conducting polymer was successfully synthesized via electropolymerization of N1,N4-bis(4-(1H-pyrrol-1-yl) phenyl)-N1,N4-diphenylbenzene-1,4-diamine (DPTPA). This polymer film exhibited six various colors

A solvent-free manganese(II) -catalyzed Clauson-Kaas protocol for the synthesis of N-aryl pyrroles under microwave irradiation

Rohit, Kizhakkekuttu Radhakrishnan,Meera, Gopinadh,Anilkumar, Gopinathan

supporting information, p. 194 - 200 (2021/10/12)

The first manganese-catalyzed modified Clauson-Kaas reaction for N-substituted pyrrole synthesis using 2,5-dimethoxytetrahydrofuran with variously substituted aromatic amines has been developed (up to 89% yield). This interesting neat strategy is free from additives including co-catalysts, ligands, and acids. Relatively low cost, environmentally benign, and handy Mn(NO3)2·4H2O is employed as the catalyst under microwave conditions with a very short reaction time (20?min). The above qualities attest to the green nature of this reaction.

AIE compound, preparation method and application in detection of organic amine

-

Paragraph 0100-0105, (2021/06/23)

The invention relates to the technical field of fluorescent materials, in particular to an AIE compound, a preparation method thereof and application of the AIE compound in organic amine detection. The structural general formula of the AIE compound is sho

A facile synthesis of 1-aryl pyrroles by clauson-Kaas reaction using oxone as a catalyst under microwave irradiation

Gullapelli, Kumaraswamy,Brahmeshwari,Ravichander

, p. 143 - 148 (2019/03/21)

A new and efficient methodology to synthesize N-substituted pyrrole derivatives by Clauson Kaas reaction employing Oxone as catalyst was developed. The transformation was performed in acetonitrile under microwave irradiation. This procedure has several advantages such as high yield, clean product formation, and short reaction time.

Solvent Free Synthesis of N-Substituted Pyrroles Catalyzed by Calcium Nitrate

Wani, Rucha R.,Chaudhari, Hemchandra K.,Takale, Balaram S.

supporting information, p. 1337 - 1340 (2019/02/05)

Moderated and mild way for synthesizing N-substituted pyrrole has been demonstrated herein. No solvents need to be used for this reaction, and instead, reactants themselves acted as a reaction medium. In fact, the reaction is carried out using catalytic amount of Ca(NO3)2.4H2O. The reaction conditions are selective and mild that helped to tolerate a wide variety of functional groups to give the desired products in good chemical yields.

MICROCAPSULES AND PROCESSES FOR THEIR PREPARATION

-

Page/Page column 33; 41; 42, (2019/06/11)

The present invention provides microcapsules encapsulating hydrophilic or hydrophobic active agents in an inorganic shell, processes for their preparation and compositions comprising them.

Nickel-Catalyzed Synthesis of N-Substituted Pyrroles Using Diols with Aryl- and Alkylamines

Singh, Khushboo,Kabadwal, Lalit Mohan,Bera, Sourajit,Alanthadka, Anitha,Banerjee, Debasis

, p. 15406 - 15414 (2019/01/04)

Herein, nickel-catalyzed sustainable strategy for the synthesis of N-substituted pyrroles using butene-1,4-diols and butyne-1,4-diols with a series of aryl-, alkyl-, and heteroarylamines is reported. The catalytic protocol is tolerant of free alcohol, halide, alkyl, alkoxy, oxygen heterocycles, activated benzyl, and the pyridine moiety and resulted in up to 90% yield. Initial mechanistic studies involving defined nickel catalyst, determination of rate, and order of reaction including deuterium-labeling experiments were performed for pyrrole synthesis.

Diels-Alder cycloadditions of N-arylpyrroles via aryne intermediates using diaryliodonium salts

Chen, Huangguan,Han, Jianwei,Wang, Limin

supporting information, p. 354 - 363 (2018/02/19)

With a strategy of the formation of benzynes by using diaryliodonium salts, a cycloaddition reaction of N-arylpyrroles with benzynes was reported. A wide range of bridge-ring amines with various substituents have been synthesized in moderate to excellent yields (35-96%). Furthermore, with a catalytic amount of TsOH·H2O, these amines can be converted into the corresponding N-phenylamine derivatives easily, which are potentially useful in photosensitive dyes.

Unveiling the Biocatalytic Aromatizing Activity of Monoamine Oxidases MAO-N and 6-HDNO: Development of Chemoenzymatic Cascades for the Synthesis of Pyrroles

Scalacci, Nicoló,Black, Gary W.,Mattedi, Giulio,Brown, Nicola L.,Turner, Nicholas J.,Castagnolo, Daniele

, p. 1295 - 1300 (2017/08/09)

A chemoenzymatic cascade process for the sustainable production of pyrroles has been developed. Pyrroles were synthesized by exploiting the previously unexplored aromatizing activity of monoamine oxidase enzymes (MAO-N and 6-HDNO). MAO-N/6-HDNO whole cell biocatalysts are able to convert 3-pyrrolines into pyrroles under mild conditions and in high yields. Moreover, MAO-N can work in combination with the ruthenium Grubbs catalyst, leading to the synthesis of pyrroles from diallylamines/-anilines in a one-pot cascade metathesis-aromatization sequence.

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