50440-88-5

Usage

Uses

Used in Pharmaceutical Industry:
2(3H)-Quinazolinone, 4-aminois used as a key intermediate in the synthesis of biologically active compounds for the pharmaceutical industry. Its role in creating potential anti-cancer and anti-inflammatory agents makes it a valuable component in drug development, contributing to the advancement of treatments for various diseases and conditions.
Used in Chemical Manufacturing:
In the chemical manufacturing industry, 2(3H)-Quinazolinone, 4-aminois utilized as a precursor for the production of dyes and pigments. Its chemical properties allow for the creation of a range of colorants used in various applications, from textiles to paints and coatings, enhancing the diversity and performance of these products.

Upstream product

• 28144-70-9 anthranilic acid amide 
• 55441-25-3 2-Cyan-phenyl-harnstoff 
• 1189-71-5 isocyanate de chlorosulfonyle 
• 1885-29-6 anthranilic acid nitrile 

Downstream Products

• 138047-82-2 2-Phenylimidazo<1,2-c>chinazolin-5(6H)-on 
• 1053698-12-6 C₃₄H₂₇N₃O₈ 
• 848830-44-4 4-amino-1-[5-deoxy-5-[(4-methoxyphenyl)thio]-2,3-O-isopropyidene-β-D-ribofuranosyl]quinozalin-2-one 
• 15135-22-5 4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one 

Relevant academic research and scientific papers

MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH

The present invention provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.

Nucleosides XI. Synthesis and antiviral evaluation of 5′-alkylthio- 5′-deoxy quinazolinone nucleoside derivatives as S-adenosyl-L-homocysteine analogs

4-Amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) was prepared by a direct glycosylation of 4-aminoquinazolin-2-one (7) using the Vorbruggen's silylation method and provided exclusively the β-anomer. This quinazoline nucleoside and its 2′,3′-O-isopropylid

EFFICIENT ENZYMATIC CYCLIZATION OF 2-(CARBAMOYLOXY)- AND 2-(SULFAMOYLOXY)BENZONITRILES BY ULTRASONICALLY STIMULATED BAKER'S YAEST

An approach to the synthesis of 4-imino substituted 1,3-benzoxazin-2-ones, 1,2,3-benzoxathiazin-2-ones and 2-quinazolinones based on the enzymatic cyclization of the labile-functionalized compounds with ultrasonically stimuled baker's yeast.

AN EFFICIENT SYNTHESIS OF 3,4-DIHYDRO-4-IMINO-2(1H)-QUINAZOLINONES

A new one-pot convenient preparation of 3,4-dihydro-4-imino-2(1H)-quinazolinones (4) is described by the reaction of 2-aminobenzonitriles (1) with chlorosulfonyl isocyanate (2), while the reaction of 1 with chlorocarbonyl isocyanate (6) affords ureidobenzonitriles (7), which on thermal cyclization gives 4.