50461-51-3 Usage
Chemical structure
Tetrahydrobipyridine compound
Pharmacological activity
Potential as a therapeutic agent for various conditions
Central nervous system
Acts as a depressant
Potential therapeutic applications
Addiction, anxiety, and pain management
Mechanism of action
Interacts with the brain's GABA receptors
Effects
Sedative and anxiolytic (anxiety-reducing) properties
Neurological disorders
Studied for potential treatment of Parkinson's disease and epilepsy
Ongoing research
Continued investigation into its therapeutic applications and potential benefits
These properties and contents are based on the information provided and highlight the compound's potential uses and areas of study.
Check Digit Verification of cas no
The CAS Registry Mumber 50461-51-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,4,6 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 50461-51:
(7*5)+(6*0)+(5*4)+(4*6)+(3*1)+(2*5)+(1*1)=93
93 % 10 = 3
So 50461-51-3 is a valid CAS Registry Number.
50461-51-3Relevant articles and documents
Design, synthesis, and evaluation of novel aryl-tetrahydropyridine PPARα/γ dual agonists
Kim, Eunkyung,Park, Chan Sun,Han, Taedong,Bae, Myung-Ho,Chong, Wonee,Lee, Choong Hyun,Shin, Young Ah,Ahn, Byung-Nak,Kim, Mi Kyung,Shin, Chang Yell,Son, Moon Ho,Kim, Jin Kwan,Moon, Ho Sang,Shim, Hyun Joo,Kim, Eun Jung,Kim, Soon Hoe,Lim, Joong In,Lee, Chun Ho
scheme or table, p. 4993 - 4996 (2009/05/26)
Aryl-tetrahydropyridine derivatives were prepared and their PPARα/γ dual agonistic activities were evaluated. Among them, compound (S)-5b was identified as a potent PPARα/γ dual agonist with an EC50 of 1.73 and 0.64 μM in hPPARα and γ, respectively. In diabetic (db/db) mice, compound (S)-5b showed good glucose lowering efficacy and favorable pharmacokinetic properties.