50488-14-7

Basic information

• Product Name: 4-oxo-4-[[3-(triethoxysilyl)propyl]amino]-2-butenoic acid
• Synonyms: 2-Butenoic acid, 4-oxo-4-((3-(triethoxysilyl)propyl)amino)-, (2Z)-; 4-Oxo-4-((3-(triethoxysilyl)propyl)amino)-2-butenoic acid (Z)-; Triethoxysilylproplmaleamic acid; 4-oxo-4-{[3-(triethoxysilyl)propyl]amino}but-2-enoic acid; (2Z)-4-oxo-4-{[3-(triethoxysilyl)propyl]amino}but-2-enoic acid; (2E)-4-oxo-4-{[3-(triethoxysilyl)propyl]amino}but-2-enoic acid
• CAS NO: 50488-14-7
• Molecular Formula: C₁₃H₂₅NO₆Si
• Molecular Weight: 319.4262
• EINECS: 251-564-1
• Mol File: 50488-14-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 439.5°C at 760 mmHg
• Flash Point: 219.6°C
• Density: 1.093g/cm³
• Vapor Pressure: 5.95E-09mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: 4-oxo-4-[[3-(triethoxysilyl)propyl]amino]-2-butenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-4-[[3-(triethoxysilyl)propyl]amino]-2-butenoic acid(50488-14-7)
• EPA Substance Registry System: 4-oxo-4-[[3-(triethoxysilyl)propyl]amino]-2-butenoic acid(50488-14-7)

Safety Data

• Hazardous Substances Data: 50488-14-7(Hazardous Substances Data)

Upstream product

• 108-31-6 maleic anhydride 
• 919-30-2 3-aminopropyltriethoxysilane 

Downstream Products

• 29602-11-7 N-(3-triethoxysilylpropyl)maleimide 

Relevant articles and documents

LCD-based detection of enzymatic action

By incorporating an ester-containing substrate in a self-assembled alignment layer for liquid crystal cells, the presence of a lipase (CALB) can be directly detected through its enzymatic action on the alignment layer, without the need for fluorescent lab

A molecular nanocap activated by superparamagnetic heating for externally stimulated cargo release

A novel thermoresponsive snaptop for stimulated cargo release from superparamagnetic iron oxide core - mesoporous silica shell nanoparticles based on a [2 + 4] cycloreversion reaction (retro-Diels Alder reaction) is presented. The non-invasive external actuation through alternating magnetic fields makes this material a promising candidate for future applications in externally triggered drug delivery.

Studies on the attachment of DNA to silica-coated nanoparticles through a Diels-Alder reaction

A new method has been investigated for the functionalization of gold nanoparticles with DNA. Silica-coated nanoparticles functionalized with a maleimide have been prepared. These particles are designed to react with modified DNA containing a diene functionality at one end of the molecule. The result would be the formation of a more stable attachment of the DNA to the particle through a Diels-Alder reaction. This covalent attachment would not be susceptible to ligand exchanges, which are known to occur in the conventional DNA functionalization of gold nanoparticles. Copyright Taylor & Francis, Inc.