505045-27-2Relevant academic research and scientific papers
Selective O-deallylation of dihydropyrazoles by molecular iodine in the presence of active N-allyl and formyl groups
Humne, Vivek T.,Hasanzadeh, Kamal,Lokhande, Pradeep D.
, p. 585 - 595 (2013/07/27)
Selective O-deallylation of dihydropyrazoles has been achieved by use of iodine (10 mol%) in PEG-400 as ecofriendly solvent. Iodine (10 mol%) in dimethyl sulfoxide at 100 C also afforded O-deallylation with aromatization compatible with highly reactive N-
One-pot synthesis of 1,3,5-triarylpyrazoles
Huang, Shufang,Ying, Huazhou,Hu, Yongzhou
, p. 478 - 483 (2013/06/27)
A series of novel 1,3,5-triarylpyrazoles were synthesized from flavanones, arylhydrazines, and trimethyl phosphate in an one-pot procedure. Facile reaction process, easy after-reaction workshop, and good yields are the distinct characteristics of the developed protocol. The target compounds were characterized by element analysis, infrared ray (IR), 1H NMR spectra, and electrospray ionization-mass spectrometry. The structure of representative compound (C23H20N2O3, Mr = 372.42) was further confirmed by X-ray diffraction. It crystallizes in monoclinic, space group P 21/c, a = 8.9720(5), b = 24.5523(13), c = 8.9687(6) A, α = 90.0000, β = 102.6417(17), γ = 90.0000°, V = 1927.76(20) A3, Z = 4, μ(MoKα) = 0.086, F(000) = 784, Dc = 1.283 g/cm3, the final R = 0.0349 and wR = 0.0844 for 1668 observed reflections (I > 2σ(I)).
