5051-49-0

Basic information

• Product Name: Benzaldehyde, 2,4-dichloro-, dimethylhydrazone
• CAS NO: 5051-49-0
• Molecular Formula: C9H10Cl2N2
• Molecular Weight: 217.098
• Mol File: 5051-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2,4-dichloro-, dimethylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2,4-dichloro-, dimethylhydrazone(5051-49-0)
• EPA Substance Registry System: Benzaldehyde, 2,4-dichloro-, dimethylhydrazone(5051-49-0)

Safety Data

• Hazardous Substances Data: 5051-49-0(Hazardous Substances Data)

Upstream product

• 874-42-0 2,4-dichlorobenzaldeyhde 
• 57-14-7 N,N-Dimethylhydrazine 

Downstream Products

• 50-84-0 2,4 dichlorobenzoic acid 
• 2447-79-2 2,4-dichlorobenzamide 
• 6574-98-7 2,4-dichlorobenzylnitrile 
• 93309-06-9 N-<1-(2,4-Dichlorphenyl)pentyl-(1)>-N'N'-dimethyl-hydrazin 
• 102146-49-6 2,4-dichlorobenzaldehyde, hydrazone 

Relevant articles and documents

3-Acryl-7-chloro-3,4-dihydro-1,9(2H, 19H) acridinedione, 1-hydrazones as potent antimalarial agents (1,2)

A series of 3-aryl-7-dihydro-1,9(2H, 10H)-acridinedione, 1-hydrazones was prepared from the corresponding acridinediones, and examined for antimalarial activity. Potent antimalarial activity against Plasmodium berghei infections in mice was found with aliphatic substituted hydrazones. Among the substituents on the phenyl ring at the 3 position of the acridine moiety particularly high activity was associated with the 4-(trifluoromethyl)phenyl group and the 2,4-dichlorophenyl group. Moreover the ring N-OH function was shown to be necessary for good biological activity. Additional structure activity relationships are also discussed.