50536-72-6 Usage
Description
3H-Benz[e]indole-2-carboxylic acid, also known as bendothiophene carboxylic acid, is a chemical compound with the molecular formula C13H9NO2. It is an aromatic carboxylic acid that features a benzene ring fused with both a five-membered and a six-membered ring, along with a carboxylic acid functional group. 3H-Benz[e]indole-2-carboxylic acid is recognized for its potential biological activities, including anti-inflammatory and anti-cancer properties, making it a compound of interest for medicinal research and development.
Uses
Used in Pharmaceutical Synthesis:
3H-Benz[e]indole-2-carboxylic acid is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable building block for creating new drugs with potential therapeutic benefits.
Used in Agrochemical Development:
In addition to its pharmaceutical applications, 3H-Benz[e]indole-2-carboxylic acid is also used in the development of agrochemicals. Its incorporation into these chemical products can contribute to the creation of more effective solutions for agricultural challenges.
Used in Medicinal Research:
Due to its potential biological activities, such as anti-inflammatory and anti-cancer properties, 3H-Benz[e]indole-2-carboxylic acid is employed in medicinal research. Researchers explore its properties to develop new treatments and therapies for various diseases and conditions.
Used in Organic Compound Synthesis:
3H-Benz[e]indole-2-carboxylic acid is also used as a building block in the synthesis of organic compounds. Its distinctive structure allows for the creation of a wide range of organic molecules for various applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 50536-72-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,5,3 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50536-72:
(7*5)+(6*0)+(5*5)+(4*3)+(3*6)+(2*7)+(1*2)=106
106 % 10 = 6
So 50536-72-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H9NO2/c15-13(16)12-7-10-9-4-2-1-3-8(9)5-6-11(10)14-12/h1-7,14H,(H,15,16)
50536-72-6Relevant articles and documents
Synthesis of 3H-Benzo[e]indoline and Its Application to Small-Molecule Organic Solar Cells
Chen, Yao,Wu, Jianglin,Yang, Lin,Hu, Bin,Yang, Daobin,Lu, Zhiyun,Huang, Yan
supporting information, p. 8747 - 8750 (2018/05/30)
A squaraine-based small molecule (USQ-BI) bearing 3H-benzo[e]indoline was synthesized as an electron donor, and the corresponding organic solar cells show power conversion efficiency of 5.35 % with an excellent short circuit current of over 15 mA cm?2. The hole mobility of USQ-BI was about 5 times (9.57×10?5 vs. 2.00×10?5 cm2 V?1 s?1) higher than that of indoline-based squaraine.
CBI analogues of the duocarmycins and CC-1065
-
Page 31, (2010/02/10)
An extensive series of CBI analogues of the duocarmycins and CC-1065 exploring substituent effects within the first indole DNA binding subunit is detailed. In general, substitution at the indole C5 position led to cytotoxic potency enhancements that can be ≧1000-fold providing simplified analogues containing a single DNA binding subunit that are more potent (IC50=2-3 pM) than CBI-TMI, duocarmycin SA, or CC-1065. The increases in cytotoxicity correlate well with accompanying increases in the rate and efficiency of DNA alkylation. This effect is more pronounced with the CBI versus DSA or CPI based analogues. Moreover, this effect is largely insensitive to the electronic character of the C5 substituent but is sensitive to the size, rigid length, and shape (sp, sp2, sp3 hybridization) of this substituent consistent with expectation that the impact is due simply to its presence.
Anti-aids piperazines
-
, (2008/06/13)
The present invention includes diaromatic substituted heterocyclic compounds (III) STR1 which are useful in treating individuals infected with the HIV virus. The invention includes certain previously generically disclosed anti-AIDS piperazinyl compounds (V) and a method of treating HIV infected individuals with the indoles of formula (V) and the anti-AIDS amines (X).
