50548-40-8

Basic information

• Product Name: 1-Dibenzofuranamine
• Synonyms: 1-Dibenzofuranamine;Dibenzofuran-1-amine;1-aminodibenzofuran;dibenzo[b,d]furan-1-amine
• CAS NO: 50548-40-8
• Molecular Formula: C₁₂H₉NO
• Molecular Weight: 183.21
• Mol File: 50548-40-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Dibenzofuranamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Dibenzofuranamine(50548-40-8)
• EPA Substance Registry System: 1-Dibenzofuranamine(50548-40-8)

Safety Data

• Hazardous Substances Data: 50548-40-8(Hazardous Substances Data)

Usage

General Description

1-Dibenzofuranamine, also known as 2-Aminodibenzofuran, is a chemical compound that consists of a dibenzofuran molecule with an amine functional group attached to it. It is used as an intermediate in the production of various chemicals such as pigments, dyes, and pharmaceuticals. The compound has been studied for its potential use in the treatment of certain medical conditions, including cancer, due to its antioxidant and anti-inflammatory properties. However, it is also important to note that 1-Dibenzofuranamine may pose health and environmental hazards and should be handled with care.

Upstream product

• 50548-45-3 1-bromodibenzo[b,d]furan 
• 533-58-4 2-Iodophenol 
• 99-65-0 meta-dinitrobenzene 
• 87812-99-5 1-nitrodibenzofuran 
• 132-64-9 dibenzofuran 
• 1332882-02-6 2,4-dinitrodibenzofuran 
• 96042-30-7 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran 
• 50548-37-3 N-(4-dibenzofuranyl)acetamide 
• 3586-12-7 3-phenoxyaniline 
• 860584-82-3 5-phenoxy-2-iodoaniline 
• 50548-38-4 1-bromo-N-(4-dibenzofuranyl)acetamide 
• 50548-39-5 1-bromodibenzo[b,d]furan-1-amine 
• 50548-43-1 4-aminodibenzofuran 

Downstream Products

• 87812-99-5 1-nitrodibenzofuran 
• 1332882-06-0 1-(2,4-diisopropyldibenzo[b,d]furan-1-yl)-2-phenyl-4,5-dihydro-1H-imidazole 
• 1332882-07-1 1-(2,4-diisopropyldibenzo[b,d]furan-1-yl)-2-phenyl-1H-imidazole 
• 857784-97-5 1-iododibenzo[b,d]furan 

Relevant articles and documents

Preparation method of 1-iododibenzofuran

The invention provides a preparation method of 1-iododibenzofuran. The preparation method comprises the following steps: adding potassium tert-butoxide, dimethyl ether and cuprous iodide into a firstreactor, stirring the mixture under the protection of nitrogen gas, adding m-dinitrobenzene dissolved with pyridine into a system, then dissolving potassium tert-butoxide and o-iodophenol with dimethyl ether, adding the dissolved mixture into the system, fully reacting under the protection of the nitrogen gas, and separating to obtain 1-nitryldibenzofuran; then adding 1-nitryldibenzofuran into a second reactor, adding ethanol, water, iron powder and ammonium chloride, fully reacting, and separating to obtain 1-aminodibenzofuran; adding the 1-aminodibenzofuran into a third reactor, then addinghydrochloric acid, dropwise adding a sodium nitrite solution and a KI solution, fully reacting, and separating to obtain 1-iododibenzofuran. The preparation method has the beneficial effects of avoidance of carrying out the reactions under an ultralow temperature reaction condition, simple and feasible synthetic method, stable productivity, higher yield and low pollution, and has remarkable advantages on the aspect of batch production.

Cu(II)-Mediated N-H and N-Alkyl Aryl Amination and Olefin Aziridination

Cu(II)-mediated direct NH2 and NH alkyl aryl aminations and olefin aziridinations are described. These room-temperature, one-pot, environmentally friendly procedures replace costly Rh2 catalysts and, in some instances, display important differences with comparable Rh2- and Fe-supported reactions.

An aryl to imidoyl palladium migration process involving intramolecular C-H activation

Biologically interesting fluoren-9-one and xanthen-9-one derivatives have been prepared by a novel aryl to imidoyl palladium migration, followed by intramolecular arylation. The fluoren-9-one synthesis appears to involve both a palladium migration mechanism and a C-H activation process proceeding through an unprecedented organopalladium(IV) hydride intermediate. The results from deuterium labeling experiments are consistent with the proposed dual mechanism.