50558-94-6Relevant academic research and scientific papers
Asymmetric Transfer Hydrogenation of Arylidene-Substituted Chromanones and Tetralones Catalyzed by Noyori-Ikariya Ru(II) Complexes: One-Pot Reduction of C═C and C═O bonds
Caleffi, Guilherme S.,Brum, Juliana De O. C.,Costa, Angela T.,Domingos, Jorge L. O.,Costa, Paulo R. R.
, p. 4849 - 4858 (2021/04/06)
3-Arylidenechroman-4-ones and 2-arylidene-1-tetralones are hydrogenated to cis-benzylic alcohols in dr's and er's up to 99:1 via a C═C and C═O one-pot reduction in the presence of 2-5 mol % Noyori-Ikariya-type RuII chiral complexes and HCO2Na as a hydroge
6-methoxy-3,4-dihydronaphthalenone chalcone-like derivatives as potent tyrosinase inhibitors and radical scavengers
Ranjbar, Sara,Akbari, Abdolhossein,Edraki, Najmeh,Khoshneviszadeh, Mahsima,Hemmatian, Hajar,Firuzi, Omidreza,Khoshneviszadeh, Mehdi
, p. 1170 - 1179 (2018/11/01)
Background: Tyrosinase is a copper-containing enzyme that involves in melanine biosynthesis and fruits enzymatic browning pathways. Chemical inhibitors of tyrosinase could have potential applications in cosmetics, medicine and food industry. In this study
2-(3′,4′-Dimethoxybenzylidene)tetralone induces anti-breast cancer activity through microtubule stabilization and activation of reactive oxygen species
Gautam, Yashveer,Dwivedi, Sonam,Srivastava, Ankita,Hamidullah,Singh, Arjun,Chanda,Singh, Jyotsna,Rai, Smita,Konwar, Rituraj,Negi, Arvind S.
, p. 33369 - 33379 (2016/05/09)
Breast cancer is a leading cause of women mortality worldwide. Diverse analogues of 2-benzylidene tetralone have been synthesized and evaluated for anti-cancer activity against a panel of cancer cell lines. Among these, compounds 13, 15 and 19 exhibited p
Synthesis, structure and antimicrobial evaluation of new 3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl-thiazol-4(5H)-ones
Gautam, Deepika,Chaudhary
, p. 219 - 226 (2014/08/18)
The reaction of semicarbazide or thiosemicarbazide with 2-arylidene-1-tetralones under alkaline condition affords 3,3a,4,5-tetrahydro- 2H-benzo[g]indazole-2-carbo(thio)amides as a mixture of cis and trans diastereoisomers of 3-H and 3a-H. The synthesis of
UV-light induced domino type reactions: Synthesis and photophysical properties of unreported nitrogen ring junction quinazolines
Palaniraja, Jeyakannu,Roopan, Selvaraj Mohana
, p. 37415 - 37423 (2015/05/20)
An expedient method for the synthesis of 5,6-dihydrobenzo[h][1,2,4]triazolo[5,1-b]quinazolines by UV light has been developed. Our aim was to synthesize various α, β-unsaturated carbonyl compounds and to further react them with different amines in DMF, in
Ionic liquid-mediated facile synthesis and antimicrobial study of thiazolo [2,3-b]benzo[h]quinazolines and thiazino[2,3-b] benzo-[h]quinazolines
Gupta, Richa,Chaudhary, Ram Pal
experimental part, p. 735 - 742 (2012/07/27)
8-Methoxy-4-phenyl-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione, obtained by the condensation of 2-benzylidene-6-methoxy-3,4-dihydronapthalene- 1(2H)-one with thiourea, on reaction with chloroacetic acid and 3-chloropropanoic acid in the presence of the ionic liquid N-methylpyridinium tosylate furnishes 3-methoxy-7-phenyl-7,10-dihydro-5H- benzo[h]thiazolo[2,3-b] quinazoline-9(6H)-one and 3-methoxy-7-phenyl-5,6,10,11-tetrahydro- benzo[h][1,3]thiazino[2,3-b]quinazoline-9(7H)-one. Further, condensation of the thione with 1,2-dibromoethane and 1,3-dibromopropane yields 3-methoxy-7-phenyl- 6,7,9,10-tetrahydro-5 H-benzo[h]thiazolo[2,3-b]quinazoline and 3-methoxy-7-phenyl-5,6,7,9,10,11-hexahydrobenzo [h][1,3]thiazino[2,3-b] quinazoline respectively. Arylidene derivatives have been obtained by two routes. The structures of the cyclized compounds have been established on the basis of elemental analysis and spectroscopic data. The synthesized compounds were screened for antimicrobial activity. Some of the compounds showed promising antimicrobial activities. Copyright
Synthesis of benzo[c]xanthones from 2-benzylidene-1-tetralones by the ultraviolet radiation-mediated tandem reaction
Xu, Wen-Zhi,Huang, Zhi-Tang,Zheng, Qi-Yu
, p. 5606 - 5608 (2008/12/21)
(Chemical Equation Presented) A facile one-pot method to prepare benzo[c]xanthones from readily accessible benzylidene-1-tetralones by the ultraviolet radiation-mediated tandem reaction is reported. The overall transformation presumably involves cis-trans
Etude de l'oxydation de tetrahydroisoquinoleinols-4 dimethoxyles en 6,7 ou 7,8, et sur la reactivite du carbonyle de la tetrahydroisoquinolone-4 dimethoxylee en 6,7
Leseche, Bernard,Gilbert, Jacques,Viel, Claude
, p. 143 - 153 (2007/10/02)
Preparation des tetrahydroisoquinoleinols-4 mentionnes ci-dessus, et etude de l'oxydation de ceux-ci au moyen de divers reactifs: oxydations chromiques, par les bromamides, le dimethylsulfoxide, la reaction d'Oppenauer.Seule cette derniere a conduit aux t
Studies in Antifertility Agents: Part XXVIII-1,2-trans-1-(p-(&β-Pyrrolidinoethoxy)phenyl)-2-substituted-benzyl-6-methoxy-1,2,3,4-tetrahydronaphthalenes
Tewari, S. C.,Rastogi, Shri Nivas
, p. 1060 - 1064 (2007/10/02)
Substituted 2-benzyl-6-methoxy-1-tetralones (8-10), obtained by catalytic hydrogenation of 2-arylidene-1-tetralones (5-7), on NaBH4 reduction give a mixture of 1,2-trans-/cis-isomers of 2-benzyl-1-tetralols (11-13).Ac2O-pyridine treatment of 11 furnishes
