50585-91-6 Usage
Uses
Used in Pharmaceutical Industry:
METHYL 1-BENZYL-PIPERIDINE-3-CARBOXYLATE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and biologically active molecules.
Used in Agrochemical Industry:
METHYL 1-BENZYL-PIPERIDINE-3-CARBOXYLATE is used as an intermediate in the synthesis of agrochemicals, playing a crucial role in the development of new compounds for agricultural applications.
Used in Organic Chemistry Research:
METHYL 1-BENZYL-PIPERIDINE-3-CARBOXYLATE is used as a building block in organic chemistry research for the preparation of a wide range of compounds, contributing to the advancement of chemical knowledge and the discovery of novel chemical entities.
Used in Medicinal Chemistry Research:
METHYL 1-BENZYL-PIPERIDINE-3-CARBOXYLATE is used as a building block in medicinal chemistry research, aiding in the design and synthesis of new therapeutic agents and enhancing the understanding of molecular interactions in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 50585-91-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,5,8 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 50585-91:
(7*5)+(6*0)+(5*5)+(4*8)+(3*5)+(2*9)+(1*1)=126
126 % 10 = 6
So 50585-91-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO2/c1-17-14(16)13-8-5-9-15(11-13)10-12-6-3-2-4-7-12/h2-4,6-7,13H,5,8-11H2,1H3
50585-91-6Relevant academic research and scientific papers
Construction of Hydroxylated Alkaloids (+/-)-Mannonolactam, (+/-)-Deoxymannojirimycin, and (+/-)-Prosopinine through Aza-Annulation
Cook, Gregory R.,Beholz, Lars G.,Stille, John R.
, p. 3575 - 3584 (2007/10/02)
The aza-annulation of β-enamino carbonyl substrates with acrylate derivatives provides an efficient and convenient route for the regioselective construction of δ-lactams.This two-step ring-forming sequence involved initial generation of the benzyl enamine through either a condensation or conjugate addition reaction with BnNH2, followed by aza-annulation with acryloyl chloride or acrylic anhydride.Controlled by the rigid framework of the intermediate lactam, introduction of ring substituents was accomplished with high relative stereoselectivity.The carbonyl functionality, which was necessary to direct the regioselectivity of the aza-annulation reaction, was then transformed into a protected hydroxyl substituent through Baeyer-Villiger oxidation.The resultant δ-lactam product was used as a valuable intermediate in the synthesis of three natural products.Subsequent modification of this δ-lactam gave the naturally occurring α-mannosidase inhibitors (+/-)-mannonolactam and (+/-)-deoxymannojirimycin, while synthesis of the alkaloid (+/-)-prosopinine was accomplished through homologation of the lactam carbonyl.
