5059-38-1

Upstream product

• 22855-03-4 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)indoline 
• 23477-48-7 1-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)indoline 
• 496-15-1 1-indoline 
• 39264-63-6 1-(β-D-galactopyranosyl)indoline 
• 5059-37-0 β-N-D-Galactopyranosyl-indol 
• 108-24-7 acetic anhydride 
• 10257-28-0 D-Galactose 
• 4163-60-4 β-D-galactose peracetate 
• 50-99-7 D-glucose 
• 2280-44-6 D-Glucose 
• 604-69-3 β-D-glucose pentaacetate 
• 39264-64-7 1-(β-D-glucopyranosyl)indoline 

Downstream Products

• 1493759-80-0 3-(4-cyclopentylphenylmethyl)-1-(β-D-glucopyranosyl)indole 
• 1493759-35-5 C₃₂H₃₅NO₉ 
• 1493759-38-8 C₃₃H₃₇NO₉ 
• 1493759-41-3 C₃₄H₃₉NO₉ 
• 1452838-63-9 3-(4-cyclopropylphenylmethyl)-1-(β-D-glucopyranosyl)indole 
• 1493759-79-7 3-(4-cyclobutylphenylmethyl)-1-(β-D-glucopyranosyl)indole 
• 1493759-13-9 C₃₄H₃₇NO₁₀ 
• 1404307-38-5 C₃₁H₃₃NO₁₀ 

Relevant academic research and scientific papers

Catalytic Aerobic Dehydrogenatin of N-Heterocycles by N-Hydoxyphthalimide

Catalytic methods for the aerobic dehydrogenation of N-heterocycles are reported. In most cases, indoles are accessed efficiently from indolines using catalytic N-hydroxyphthalimide (NHPI) as the sole additive under air. Further studies revealed an improved catalytic system of NHPI and copper for the preparation of other heteroaromatics, for example quinolines. (Figure presented.).

Novel indole-N-glucoside, TA-1887 As a sodium glucose cotransporter 2 inhibitor for treatment of type 2 diabetes

Inhibition of the renal sodium glucose cotransporter (SGLT) increases urinary glucose excretion (UGE) and thus reduces blood glucose levels during hyperglycemia. To explore the potential of new antihyperglycemic agents, we synthesized and determined the h

Synthesis of 1,3- and 2,3-diglycosylated indoles as potential trisaccharide mimetics

Diglycosylated heteroaromatics may serve as metabolically stable mimetics of trisaccharides. Herein, the preparation of several 1,3- and 2,3-diglycosylindoles by direct C-glycosylation of monoglycosylated precursors is described. Georg Thieme Verlag Stuttgart ? New York.

Sweet (hetero)aromatics: Glycosylated templates for the construction of saccharide mimetics

Mono- and diglycosylated aromatics and heteroaromatics may serve as building blocks for the construction of metabolically stable mimetics of oligosaccharides. Methods for their preparation from monosaccharidic precursors by direct C-glycosylation, dipolar cycloaddition or Larock cyclization are described.

1-( -D-GLYCOPYRANOSYL)-3-SUBSTITUTED NITROGENOUS HETEROCYCLIC COMPOUND, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF

A compound having SGLT1 and/or SGLT2 inhibitory activity which is usable as an agent for the prevention or treatment of diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, obesity, etc. It is a 1-(β-D-glycopyranosyl)-3-substituted nitrogen-containing heterocyclic compound represented by the general formula (I), a prodrug, or a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof; an SGLT inhibitor containing the same; a pharmaceutical composition containing the same and a medicinal use thereof. In the formula, ring A represents optionally substituted aryl or heteroaryl; Q1 to Q5 independently represent a carbon atom having a hydrogen atom or substituent bonded thereto or a nitrogen atom; E represents a single bond, alkylene, -O-, -S- or -NH-; and R.represents methyl, ethyl, fluoromethyl or hydroxymethyl.

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives

In the course of structure-activity relationship studies, diversely substituted 1-(β-D-glucopyranosyl)-isoindigo derivatives were prepared from commercially available indolines. Their antiproliferative activities were evaluated toward a panel of human solid cancer cell lines (PC 3, DLD-1, MCF-7, M4Beu, A549, PA 1), a murine cell line (L929) and a human fibroblast primary culture to get an insight into the substitution pattern required for the best biological potencies.

Synthesis of 1-glycosyl derivatives of benzocamalexin

The linear synthesis of 1-(β-o-glucopyranosyl)-, 1-(β-D- galactopyranosyl)-, 1-(β-D-mannopyranosyl)- and 1-(β-D-ribofuranosyl) benzocamalexin was elaborated from indoline as a starting compound and corresponding pentaacetylhexoses or 1-O-acetyl-2,3,5-tri-