506-45-6

Basic information

• Product Name: 22-hydroxydocosanoic acid
• Synonyms: docosanoic acid, 22-hydroxy-
• CAS NO: 506-45-6
• Molecular Formula: C₂₂H₄₄O₃
• Molecular Weight: 356.583
• Mol File: 506-45-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 491.6°C at 760 mmHg
• Flash Point: 265.2°C
• Density: 0.929g/cm³
• Vapor Pressure: 1E-11mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: 22-hydroxydocosanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 22-hydroxydocosanoic acid(506-45-6)
• EPA Substance Registry System: 22-hydroxydocosanoic acid(506-45-6)

Safety Data

• Hazardous Substances Data: 506-45-6(Hazardous Substances Data)

Usage

Description

22-hydroxy Docosanoic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark as well as the leaves, roots, and wood of Q. ilex from Cala Violina and Colognole, Italy. [Matreya, LLC. Catalog No. 1818]

Uses

22-?Hydroxydocosanoic Acid is a lipophilic extract from Acacia dealbata which may be used in improving the hydrophobicity of suberin fatty acids.

Upstream product

• 7511-30-0 1,20-eicosanedicarboxylic acid monomethyl ester 
• 22399-98-0 docosanedioic acid dimethyl ester 
• 2777-65-3 undec-10-ynoic acid 
• 177177-92-3 22-benzyloxydocosanoic acid 
• 96303-14-9 22-(tetrahydropyran-2-yloxy)-10,12-docosadiynoic acid 
• 13030-63-2 11-bromo-10-undecynoic acid 
• 2774-84-7 undec-10-yn-1-ol 
• 2777-66-4 methyl 10-undecynoate 
• 96303-15-0 22-(tetrahydropyran-2-yloxy)docosanoic acid 
• 97157-86-3 Phellochrysein; Phloiorubein 

Downstream Products

• 78774-39-7 22-Brom-docosansaeure 

Relevant articles and documents

Macrolactonization Reactions Driven by a Pentafluorobenzoyl Group**

Macrolactones constitute a privileged class of natural and synthetic products with a broad range of applications in the fine chemicals and pharmaceutical industry. Despite all the progress made towards their synthesis, notably from seco-acids, a macrolactonization promoter system that is effective, selective, flexible, readily available, and, insofar as possible, compatible with manifold functional groups is still lacking. Herein, we describe a strategy that relies on the formation of a mixed anhydride incorporating a pentafluorophenyl group which, due to its high electronic activation enables a convenient access to macrolactones, macrodiolides and esters with a broad versatility. Kinetic studies and DFT computations were performed to rationalize the reactivity of the pentafluorophenyl group in macrolactonization reactions.

DEPOLYMERIZATION EXTRACTION OF COMPOUNDS FROM BIRCH BARK

The invention provides improved processes for the extraction of betulin, lupeol, betulinic acid, suberinic acids, and/or other organic compounds and compositions from birch bark.

Syntheis of the linoleic acid esters of some unsaturated long-chain ω-hydroxy fatty acids

The (Z)-32-hydroxy-23-Dotriacontenoic acid ester of linoleic acid (19), a compound implicated in skin metabolism, and related compounds have been synthesized in a nine-steps scheme, starting from 10-undecynoic acid.Overall yield amounted to 5.2percent.