50605-62-4Relevant academic research and scientific papers
Synthesis of a carbocyclic sialic acid analogue for the inhibition of influenza virus neuraminidase
Bianco, Armandodoriano,Brufani, Mario,Manna, Fedele,Melchioni, Cristiana
, p. 23 - 31 (2001)
The influenza virus neuraminidase (NA) is essential for viral infection and offers a potential target for antiviral drug development. We prepared a carbocyclic sialic acid analogue, potentially able to inhibit NA. Its structure is an analogue of the trans
An efficient transformation of (-)-quinic acid into carba-L-rhamnose
Valsecchi, Elena,Tacchi, Alessio,Prosperi, Davide,Compostella, Federica,Panza, Luigi
, p. 2529 - 2532 (2007/10/03)
A novel stereoselective synthesis of carba-L-rhamnose from (-)-quinic acid is described. The title compound is obtained with an appropriate pattern of protecting groups to be used for the preparation of Streptococcus pneumoniae type 19F capsular polysacch
