5062-66-8

Usage

Uses

Used in Chemical Industry:
1-Aminocyclopentane-1-methanamine is used as a chemical intermediate for the synthesis of various compounds and materials. Its strong base properties allow it to participate in a range of chemical reactions, making it a valuable component in the production of specialty chemicals and pharmaceuticals.
Used in Pharmaceutical Industry:
1-Aminocyclopentane-1-methanamine is used as a building block in the development of new drugs and pharmaceuticals. Its unique structure and reactivity can be exploited to create novel molecules with potential therapeutic applications.
Used in Research and Development:
1-Aminocyclopentane-1-methanamine is used as a research compound in academic and industrial laboratories. Its properties and reactivity are studied to gain insights into new chemical reactions and to develop innovative applications in various fields.

InChI:InChI=1/C6H14N2/c7-5-6(8)3-1-2-4-6/h1-5,7-8H2

Upstream product

• 5009-09-6 N-(1-cyanocyclopentyl)acetamide 
• 120-92-3 cyclopentanone 
• 1383777-45-4 1-(aminomethyl)-N-benzylcyclopentanamine 
• 289895-99-4 1-(benzylamino)cyclopentanecarbonitrile 
• 17193-28-1 1-aminocyclopentane-1-carboxamide 
• 912770-99-1 (1-cyanocyclopentyl)-carbamic acid tert-butyl ester 
• 889949-09-1 (1-aminomethylcyclopentyl)carbamic acid tert-butyl ester 
• 1204616-80-7 1-amino-1-(nitromethyl)cyclopentane 

Downstream Products

• 13157-23-8 1,3-diaza-spiro[4.4]nonane-2-thione 
• 5062-75-9 1-((dimethylamino)methyl)-N,N-dimethylcyclopentanamine 

Relevant academic research and scientific papers

Palladium-Catalyzed Modular Synthesis of Substituted Piperazines and Related Nitrogen Heterocycles

We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction. The process couples two of the carbons of a propargyl unit with various diamine components to provide nitrogen heterocycles in generally good to excellent yields and high regio- and stereochemical control. (Chemical Equation Presented).

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

PYRIMIDINONE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF

The invention relates to novel products of formula (Ia) or (Ib): these products being in all the isomeric forms and salts as drugs, notably as anticancer drugs.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Organic Compounds

A compound of Formula I in free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Method for producing 1,1-disubstituted ethylenediamine

[PROBLEM TO BE SOLVED]: To provide a method for synthesizing 1,1-disubstituted ethylenediamine (III) safely and economically, and therefore making possible a industrial production. [SOLUTION]: The method for producing the intermediate shown by the general formula (II) characterized by reacting ketones shown by the general formula (I) , nitromethane and ammonia, next producing 1,1-disubstituted ethylenediamine shown by the general formula (III) by catalytic hydrogenation's reaction.(Wherein R1, R2 are at the same time or independently alkyl of C1-6, trifluoromethyl, or cycloalkyl of 3-10 formed by R1 and R2 and the carbon of the root.)