50620-98-9Relevant academic research and scientific papers
Investigation on the coordination mode of IL-supported diols used as phosphine-free ligands for palladium catalyzed heck reaction
Cai, Yueqin,Song, Gonghua,Chen, Xiao
, p. 1250 - 1256 (2013)
The coordination mode of IL-supported diols used as phosphine-free ligands for palladium catalyzed Heck reaction has been investigated by tuning their compositions. The difference in coordination of these IL-supported diols with metal Pd in Heck reaction was related to the changes of the cation rings, leading to the different activities of Pd catalyst in the reaction. The experimental results indicated that the activities of Pd catalyst were affected mainly by π-electron density of the cation rings. Compared to pyridinium and piperidinium cations, imidazolium cations showed the best coordination to metal Pd. In the meantime, C-2 hydrogen and the length of alkyl side chains had impacts on the coordination as well. Copyright
Bioactivity and structure-activity relationship of cinnamic acid esters and their derivatives as potential antifungal agents for plant protection
Zhou, Kun,Chen, Dongdong,Li, Bin,Zhang, Bingyu,Miao, Fang,Zhou, Le
, (2017/04/26)
A series of cinnamic acid esters and their derivatives were synthesized and evaluated for antifungal activities in vitro against four plant pathogenic fungi by using the mycelium growth rate method. Structure-activity relationship was derived also. Almost all of the compounds showed some inhibition activity on each of the fungi at 0.5 mM. Eight compounds showed the higher average activity with average EC50 values of 17.4-28.6 μg/mL for the fungi than kresoxim-methyl, a commercial fungicide standard, and ten compounds were much more active than commercial fungicide standards carbendazim against P. grisea or kresoxim-methyl against both P. grisea and Valsa Mali. Compounds C1 and C2 showed the higher activity with average EC50 values of 17.4 and 18.5 μg/mL and great potential for development of new plant antifungal agents. The structure-activity relationship analysis showed that both the substitution pattern of the phenyl ring and the alkyl group in the alcohol moiety significantly influences the activity. There exists complexly comprehensive effect between the substituents on the phenyl ring and the alkyl group in the alcohol moiety on the activity. Thus, cinnamic acid esters showed great potential the development of new antifungal agents for plant protection due to high activity, natural compounds or natural compound framework, simple structure, easy preparation, low-cost and environmentally friendly.
Palladium supported on zinc oxide nanoparticles: Synthesis, characterization, and application as heterogeneous catalyst for Mizoroki-Heck and Sonogashira reactions under ligand-free and air atmosphere conditions
Hosseini-Sarvari, Mona,Razmi, Zahra,Doroodmand, Mohammad Mehdi
, p. 477 - 486 (2014/03/21)
In this paper, a novel Palladium (Pd) supported on ZnO nanoparticles was readily synthesized and characterized by using X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and BET specific surface area measurement. The total amount of palladium particles on ZnO was determined by induced coupled plasma (ICP) analysis and atomic absorption spectroscopy (AAS) which is 9.8 wt%. Percentage of accessible Pd as active catalyst is also estimated to 2.72% based on the thermogravimetric (TG) analysis. Nano Pd/ZnO was found as a new, novel, and excellent heterogeneous catalyst for ligand-free C-C bond formation through the Mizoroki-Heck and Sonogashira reactions under air atmosphere without the use of any Ar or N2 flow. The catalyst can be recovered and recycled several times without marked loss of activity.
Preparation of active and robust palladium nanoparticle catalysts stabilized by diamine-functionalized mesoporous polymers
Xing, Rong,Liu, Yueming,Wu, Haihong,Li, Xiaohong,He, Mingyuan,Wu, Peng
supporting information; scheme or table, p. 6297 - 6299 (2009/04/13)
A two-step chemical modification process is designed for synthesizing novel diamine-functionalized mesopolymers, which combine the advantage of organic polymers and mesoporous materials, and serve as an efficient scaffold for supporting highly dispersed, catalytically active and robust Pd nanoparticles (NPs). The Royal Society of Chemistry 2008.
6-Membered heterocyclic compound and use thereof
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Page/Page column 206, (2008/06/13)
A compound represented by the general formula (I) or a salt thereof: [T represents oxygen atom and the like; V represents CH2 and the like; RO1 to RO4 represent hydrogen atom and the like; A represents a linear alkylene group or linear alkenylene group having 2 to 8 carbon atoms and the like; D represents carboxyl group and the like; X represents ethylene group, trimethylene group and the like; E represents —CH(OH)— group and the like; and W represent —U1—(RW1)(RW2)—U2—U3 group (U1 represents a single bond, an alkylene group having 1 to 4 carbon atoms and the like; RW1 and RW2 represent hydrogen atom and the like; U2 represents a single bond, an alkylene group having 1 to 4 carbon atoms and the like; and U3 represent an alkyl group having 1 to 8 carbon atoms and the like), or a residue of a carbon ring or heterocyclic compound], which can be utilized as an active ingredient of medicaments effective for prophylactic and/or therapeutic treatment of skeletal diseases such as osteoporosis and fracture, glaucoma, ulcerative colitis and the like.
