50634-27-0

Upstream product

• 100-67-4 potassium phenolate 
• 135081-27-5 4-chloro-3'-methylsulfanyl-3,4'-diquinolinyl sulfide 
• 154385-00-9 1,4-dihydro-4-oxo-3'-benzylthio-3,4'-diquinolinyl sulfide 

Downstream Products

• 21626-51-7 N-(4-methylphenyl)quinolin-4-amine 
• 21626-50-6 quinolin-4-yl-o-tolyl-amine 
• 97819-53-9 9-chloro-12(H)-quino[3,4-b][1,4]benzothiazine 
• 30696-07-2 phenyl-quinolin-4-yl-amine 
• 97819-50-6 12H-quino<3,4-b>-1,4-benzothazine 
• 157494-40-1 4-chloro-3-quinolinesulfonyl chloride 
• 109179-10-4 2-[3-(3-Methylsulfanyl-quinolin-4-ylsulfanyl)-quinolin-4-yl]-cyclohexanone 
• 109179-14-8 [3-(3-Ethylsulfanyl-quinolin-4-ylsulfanyl)-quinolin-4-yl]-phenyl-acetonitrile 
• 109179-13-7 [3-(3-Methylsulfanyl-quinolin-4-ylsulfanyl)-quinolin-4-yl]-phenyl-acetonitrile 
• 83936-05-4 1-methyl-1,4-dihydro-4-oxo-3'-benzylthio-3,4'-diquinolinyl sulfide 
• 154384-98-2 4-methoxy-3-(benzylthio)quinoline 
• 146331-29-5 3',4-dibenzylthio-3,4'-diquinolinyl sulfide 
• 109179-11-5 2-[3-(3-Methylsulfanyl-quinolin-4-ylsulfanyl)-quinolin-4-yl]-1-phenyl-ethanone 
• 154841-56-2 C₂₆H₂₀N₂OS₂ 

Relevant academic research and scientific papers

4-Substituted 3-methylsulfanyl-5-, 6-, and 8-nitro-quinolines from nitro derivatives of 4-substituted 3′-methylsulfinyl-3,4′-diquinolinyl sulfides

Potassium phenoxide reacted with 4-substituted 3′-methylsulfanyl-3,4′-diquinolinyl sulfides (1 or 3) at the substituent at the C4 position. 3′-Methylsulfinyl group promotes nucleophilic substitution of 4′-quinolinyl sulfur bond in sulfoxides (2) and (4) i

Reactions of 4-methoxy-3-quinolinyl and 1,4-dihydro-4-oxo-3-quinolinyl sulfides aiming at the synthesis of 4-chloro-3-quinolinyl sulfides [1]

The preparation of 1,4-dihydro-4-oxo-3'-alkylthio-3,4'-diquinolinyl sulfides 3 or 1,4-dihydro-4-oxo-3-(alkylthio)quinolines 4 by acid catalysed hydrolysis of 4-methoxy-3'-alkylthio-3,4'-diquinolinyl sulfides 1 or 4- methoxy-3-(alkylthio)-quinolines 2 is described. The reactions of 4-methoxy- 3'-alkylthio-3,4'-diquinolinyl sulfides 1 or 1,4-dihydro-4-oxo-3'-alkylthio- 3,4'-diquinolinyl sulfides 3 with phosphoryl chloride in DMF afforded 4- chloro-3'-alkylthio-3,4'-diquinolinyl sulfides 5. Treatment of the title compounds 1 or 3 with boiling phosphoryl chloride systems: leads to 4- chloro-3-(alkylthio)quinolines 6 and thioquinanthrene but those of alkoxy- or oxo-quinolines 2 or 4 lead to 4-chloro-3-(alkylthio)quinolines 6. The reactions of N-methyl-4(1H)-quinolinones 3n and 4n with phosphoryl chloride directed to 4-chloro-3-(alkylthio)quinolines 6 were studied as well.