157494-40-1Relevant articles and documents
Preparation and oxidative-chlorination splitting of nitro derivatives of 1,4-dithiino[2,3-c:5,6-c′]diquinoline as a source of 4-substituted 5-and 8-nitro-3-quinolinesulfonic acid derivatives
Chrobak, Elwira,Maslankiewicz, Andrzej,Chycko, Magdalena,Skrzypek, Leszek,Szmielew, Magorzata,Maslankiewicz, Maria J.,Kusz, Joachim,Zubko, Maciej
experimental part, p. 1208 - 1225 (2012/10/08)
Treatment of 1,4-dithiino[2,3-c:5,6-c]diquinoline (a thioquinanthrene) (1a) with an excess of nitrating mixture (0 C, 14days) led to a mixture of mono-and dinitrothioquinanthrene 7-oxides 2b-e and 2f-h. This mixture was: (i) reduced to a mixture of mono-and dinitrothioquinanthrenes 1b-e, or (ii) oxidatively chlorinated with a gaseous chlorine/80% acetic acid/hydrochloric acid system to a mixture of 4-chloro-3-chlorosulfonylquinoline 3a and its 5-and 8-nitroderivatives 3b and 3d. Sulfochlorides 3a-d were independently synthesized from 3,4-diquinolinyl sulfides 4 and converted to the respective 4-dimethylamino-3-quinoline-N,N-dimethylsulfonamides 9a-d. Taylor and Francis Group, LLC.
Synthesis and Amination of 4-Chloro-3-quinolinesulfonyl Chloride
Maslankiewicz, Andrzej,Skrzypek, Leszek
, p. 1317 - 1332 (2007/10/02)
Chlorinolysis of 4-chloro-3-benzylthioquinoline (2) or thoquinanthrene (1) using chlorine gas in the presence of water gave 4-chloro-3-quinolinesulfonyl chloride (3).Amination of (3) performed in ether led to 4-chloro-3-quinolinesulfonamides (4).Reactions