157494-40-1

Upstream product

• 74575-22-7 C₉H₇NS₂ 
• 146945-02-0 thioquinanthrene sulfoxide 
• 83936-10-1 4-chloro-3-(benzylthio)quinoline 
• 50634-27-0 1,4-dithiino[2,3-c:5,6-c']diquinoline 

Downstream Products

• 157494-13-8 4-Chloro-quinoline-3-sulfonic acid phenylamide 
• 157494-22-9 4-Phenylamino-quinoline-3-sulfonic acid phenylamide 
• 157494-18-3 4-Chloro-quinoline-3-sulfonic acid methyl-phenyl-amide 
• 1098109-38-6 sodium 4-benzylsulfanyl-3-quinolinesulfinate 
• 1098109-47-7 4-benzylsulfanyl-3-phenylmethanesulfonylquinoline 
• 1098109-43-3 4-methylsulfanyl-3-phenylmethanesulfonylquinoline 
• 157494-32-1 4-Methylamino-quinoline-3-sulfonic acid phenylamide 
• 21626-51-7 N-(4-methylphenyl)quinolin-4-amine 
• 5895-77-2 ethyl-quinolin-4-yl-amine 
• 30696-07-2 phenyl-quinolin-4-yl-amine 
• 16401-66-4 N-methylquinolin-4-amine 
• 205985-49-5 4-chloro-3-quinolinesulfonic acid 

Relevant academic research and scientific papers

Preparation and oxidative-chlorination splitting of nitro derivatives of 1,4-dithiino[2,3-c:5,6-c′]diquinoline as a source of 4-substituted 5-and 8-nitro-3-quinolinesulfonic acid derivatives

Treatment of 1,4-dithiino[2,3-c:5,6-c]diquinoline (a thioquinanthrene) (1a) with an excess of nitrating mixture (0 C, 14days) led to a mixture of mono-and dinitrothioquinanthrene 7-oxides 2b-e and 2f-h. This mixture was: (i) reduced to a mixture of mono-and dinitrothioquinanthrenes 1b-e, or (ii) oxidatively chlorinated with a gaseous chlorine/80% acetic acid/hydrochloric acid system to a mixture of 4-chloro-3-chlorosulfonylquinoline 3a and its 5-and 8-nitroderivatives 3b and 3d. Sulfochlorides 3a-d were independently synthesized from 3,4-diquinolinyl sulfides 4 and converted to the respective 4-dimethylamino-3-quinoline-N,N-dimethylsulfonamides 9a-d. Taylor and Francis Group, LLC.

From 2,3-, 2,6-, 3,4- and 4,6-dichloroquinolines to isomeric chloroquinolinesulfonyl chlorides

The action of sodium methanethiolate (in boiling DMF) on x,y-dichloroquinolines (1) (x=3 or 6, y=2 or 4) occured via chlorine ipso-substitution followed by methanethiolato-S-demethylation to yield x,y-quinolinedithiolates 2A which were: i) subjected to S-

Synthesis and Amination of 4-Chloro-3-quinolinesulfonyl Chloride

Chlorinolysis of 4-chloro-3-benzylthioquinoline (2) or thoquinanthrene (1) using chlorine gas in the presence of water gave 4-chloro-3-quinolinesulfonyl chloride (3).Amination of (3) performed in ether led to 4-chloro-3-quinolinesulfonamides (4).Reactions