506423-93-4

Usage

Class of organic compounds

pyridinedicarboxaldehydes This indicates the family of compounds to which 2,6-Pyridinedicarboxaldehyde, 4-methyl(9CI) belongs.

Use in synthesis

pharmaceuticals and organic compounds This indicates that 2,6-Pyridinedicarboxaldehyde, 4-methyl(9CI) is used as a building block or intermediate in the synthesis of other compounds, specifically in the pharmaceutical and agrochemical industries.

High reactivity

versatile intermediate in organic synthesis This indicates that 2,6-Pyridinedicarboxaldehyde, 4-methyl(9CI) is known for its high reactivity, making it a useful intermediate in organic synthesis.

Potential health hazards

handle with care This indicates that 2,6-Pyridinedicarboxaldehyde, 4-methyl(9CI) may pose potential health hazards and should be handled with care in a controlled environment.

InChI:InChI=1/C8H7NO2/c1-6-2-7(4-10)9-8(3-6)5-11/h2-5H,1H3

Upstream product

• 108-75-8 2,4,6-trimethyl-pyridine 
• 506423-84-3 2,6-bis(hydroxymethyl)-4-methylpyridine 
• 107144-76-3 2,6-dibenzylidene-4-methylpyridine 
• 4566-82-9 dimethyl 4-methylpyridine-2,6-dicarboxylate 

Downstream Products

• 110442-30-3 4-methyl-pyridine-2,6-dicarbaldehyde bis-(2-hydroxy-phenylimine) 
• 37645-36-6 4-methyl-2,6-pyridinedicarboxylic acid 

Relevant academic research and scientific papers

Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds

CADA compounds selectively down-modulate human cell-surface CD4 protein and are of interest as HIV entry inhibitors and as drugs for asthma, rheumatoid arthritis, diabetes and some cancers. Postulating that fusing a pyridine ring bearing hydrophobic subst

Synthesis of dicyanopyridines

Synthesis of the title compounds in four steps using inexpensive collidine and lutidine as starting materials is described.

Concave pyridines with extended π-systems

New 4-substituted concave pyridines 1b-d have been synthesised as precursors to allow extension of the pyridine π-system. With the Sonogashira coupling as the key synthetic step, the 4-iodo pyridine 1c was coupled with phenylacetylene (11) to give 1g in 77% yield. Because of its conjugated π system, the new concave pyridine 1g has UV absorption maxima at λmax1 = 286 nm and λmax2 = 303 nm with εmax1 = 43300 Lmol-1cm-1 and εmax2 = 39300 Lmol-1cm-1, respectively, allowing its potential application as a sensor. ( Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002).