50656-04-7

Basic information

• Product Name: 4-benzonitrile
• Synonyms: 4-benzonitrile
• CAS NO: 50656-04-7
• Molecular Weight: 255.707
• Mol File: 50656-04-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzonitrile(50656-04-7)
• EPA Substance Registry System: 4-benzonitrile(50656-04-7)

Safety Data

• Hazardous Substances Data: 50656-04-7(Hazardous Substances Data)

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 100-63-0 phenylhydrazine 
• 100726-23-6 4-((2-phenylhydrazono)methyl)benzonitrile 
• 6068-72-0 4-cyanobenzoyl chlorIde 
• 88405-47-4 p-cyano-N'-phenylbenzohydrazine 

Downstream Products

• 1251005-02-3 (3aR,6aR,3a'S,6a'S)-4,4'-[oxybis[(4,1-phenylene)(3a,4,6,6a-tetrahydro-4,6-dioxo-1-phenylpyrrolo[3,4-c]pyrazole-5,3(1H)-diyl)]]bis[benzonitrile] 
• 1251005-19-2 (3aR,6aR,3a'S,6a'S)-4,4'-[(4,1-phenylene)bis(3a,4,6,6a-tetrahydro-4,6-dioxo-1-phenylpyrrolo[3,4-c]pyrazole-5,3(1H)-diyl)]bis[benzonitrile] 
• 1251004-76-8 (3aR,6aR,3a'S,6a'S)-4,4'-[methylenebis[(4,1-phenylene)(3a,4,6,6a-tetrahydro-4,6-dioxo-1-phenylpyrrolo[3,4-c]pyrazole-5,3(1H)-diyl)]]bis[benzonitrile] 
• 1354908-63-6 4-[(3aS,6aS)-1,3a,4,5,6,6a-hexahydro-4,6-dioxo-1-phenyl-5-[(1R)-1-phenylethyl]pyrrolo[3,4-c]pyrazol-3-yl]benzonitrile 
• 67223-85-2 4-(1,5,5-triphenyl-4,5-dihydro-1H-pyrazol-3-yl)-benzonitrile 
• 67223-81-8 4-(1,5-diphenyl-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile 

Relevant articles and documents

Sequential [3+2] annulation reaction of prop-2-ynylsulfonium salts and hydrazonyl chlorides: Synthesis of pyrazoles containing functional motifs

A novel sequential [3+2] annulation reaction has been developed using prop-2-ynylsulfonium salts and hydrazonyl chlorides, affording a series of pyrazoles with functional motifs that can be post modified in the preparation of various drugs or drug candidates. Further transformation and gram-scale operations could also be achieved efficiently. This journal is

Synthesis, UV-Vis spectra, and Hammett correlation of some novel bis(dihydropyrrolo[3,4-c]pyrazoles)

Twenty-nine novel bis(dihydropyrrolo[3,4-c]pyrazole) derivatives were obtained by reacting C, N-phenyl-substituted nitrilimines generated in situ from corresponding hydrazonyl chlorides with bismaleimides. The structures were elucidated by physical and spectroscopic methods [m.p., Rf, infrared (IR),1H nuclear magnetic resonance (NMR), 13C NMR, correlation spectroscopy (COSY), heteronuclear correlation (HETCOR), nuclear Overhauser effect (NOE), and high-resolution mass spectrometry (HRMS)]. Also, Hammett correlation graphs were obtained between Hammett constants σp and λmax values of bis(pyrrolopyrazoles) carrying p-substituted phenyl-ring-bearing electron-withdrawing and electrondonating groups and discussed in terms of substituent effects. Springer-Verlag 2010.