50684-88-3Relevant academic research and scientific papers
A direct catalytic aldol route to protected β-hydroxy-α-amino acids
Willis, Michael C.,Piccio, Vincent J.-D.
, p. 1625 - 1628 (2002)
The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuab
The direct catalytic enantioselective synthesis of protected aryl β-hydroxy-α-amino acids
Willis, Michael C.,Cutting, Gary A.,Piccio, Vincent J.-D.,Durbin, Matthew J.,John, Matthew P.
, p. 1543 - 1545 (2007/10/03)
The combination of three reagents-a tridentate pybox ligand (pybox = pyridine bis(oxazoline)), magnesium perchlorate, and Huenig base (iPr 2EtN)-allows the catalytic generation of a chiral glycine enolate from 1 that undergoes highly enantiosel
