50685-29-5Relevant academic research and scientific papers
A simple method for the rapid synthesis of 2-amino-7,7-dimethyl-5-oxo-1,4-diaryl-hexahydroquinoline-3-carboxamide derivatives
Hosseini, Fahimeh Sadat,Bayat, Mohammad
, p. 2267 - 2274 (2020/05/19)
Abstract: Simple synthesis of oxoquinoline carboxamide derivatives via one-pot, multi-component reaction of enaminones derived from the addition of dimedone to various anilines with aromatic aldehydes and cyanoacetamide is described. Optimal reaction cond
Catalyst-free Synthesis of Tetrahydroacenaphtho[1,2-b]indolone Derivatives via One-pot Four-component Reaction
Bayat, Mohammad,Amiri, Zeinab
, p. 1346 - 1351 (2018/04/14)
A simple and efficient one-pot synthesis of tetrahydroacenaphtho[1,2-b]indolone derivatives via four-component reaction of 5,5-dimethylcyclohexane-1,3-dione (dimedone), arylamines, acenaphthoquinone, and active methylene compounds under catalyst-free conditions is described. The reactions were carried out under mild conditions using ethanol as solvent. Advantages of this method include simple experimental and workup procedure, readily available starting materials, and high yields.
Iodine(III)-Promoted Ring Contractive Cyanation of Exocyclic β-Enaminones for the Synthesis of Cyanocyclopentanones
Bhattacherjee, Dhananjay,Thakur, Vandna,Sharma, Saurabh,Kumar, Sandeep,Bharti, Richa,Reddy, C. Bal,Das, Pralay
supporting information, p. 2209 - 2214 (2017/07/07)
A highly efficient hypervalent iodine-promoted regiocontrolled ring contractive cyanation (RCC) reaction of exocyclic β-enaminones for the synthesis of cyanocyclopentanone (CCP) was demonstrated at ambient temperature with a wide substrate scope. The meth
Silica sulfuric acid-mediated synthesis of β-enaminones and β-enaminoesters under microwave irradiation
Datta, Bandita,Pasha
experimental part, p. 171 - 177 (2011/04/22)
Silica sulfuric acid, a heterogeneous reagent, has been found to be an efficient catalyst for the synthesis of β-enaminones and β-enaminoesters under microwave irradiation in a microwave reactor within 2 min. The experimental procedure is simple and environment-friendly, and results in excellent yields of the products. Further, the catalyst is recyclable, and the reaction is 60 times faster than the reaction at room temperature. Copyright Taylor & Francis Group, LLC.
Molecular iodine-catalyzed mild and effective synthesis of β-enaminones at room temperature
Datta, Bandita,Reddy, M. B. Madhusudana,Pasha
experimental part, p. 2331 - 2336 (2011/06/27)
Molecular iodine has been found to be an efficient and ecofriendly catalyst for the synthesis of β-enaminones from dimedone and amines at room temperature in the presence of acetonitrile within 60 min. The experimental procedure is simple, includes shorter reaction times, and results in excellent yields of the products. Copyright
5-QUINOLINONE AND IMIDAZOPYRIDINE COMPOUNDS AND USE THEREOF
-
Page/Page column 16, (2010/04/03)
5-Quinolinone and Imidazopyrimidine compounds are provided that are useful for inhibiting the efflux of any therapeutic agent that is a MRP1 substrate. Also provided is a method for screening to identify additional MRP1 inhibitors.
