50689-17-3

Basic information

• Product Name: 3-chlorofuran
• Synonyms: 3-chlorofuran
• CAS NO: 50689-17-3
• Molecular Formula: C₄H₃ClO
• Molecular Weight: 102.51902
• EINECS: 256-715-5
• Mol File: 50689-17-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 109.03°C (rough estimate)
• Flash Point: 0.9°C
• Appearance: /
• Density: 1.2094
• Vapor Pressure: 105mmHg at 25°C
• Refractive Index: 1.4601 (estimate)
• CAS DataBase Reference: 3-chlorofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chlorofuran(50689-17-3)
• EPA Substance Registry System: 3-chlorofuran(50689-17-3)

Safety Data

• Hazardous Substances Data: 50689-17-3(Hazardous Substances Data)

Usage

General Description

3-chlorofuran is a chemical compound with the molecular formula C4H3ClO. It is a clear, colorless liquid with a faint, sweet odor and is used primarily as an intermediate in the manufacture of pesticides and pharmaceuticals. 3-chlorofuran is considered to be highly flammable and can cause eye and skin irritation upon contact. It is also a known respiratory irritant and may cause drowsiness or dizziness after exposure. The compound is also known to be harmful if swallowed and can cause serious damage to aquatic life. 3-chlorofuran is considered to have moderate acute toxicity and is a potential environmental hazard.

InChI:InChI=1/C4H3ClO/c5-4-1-2-6-3-4/h1-3H

Upstream product

• 66204-31-7 3-chlorofuran-2-carboxylic acid 
• 22037-28-1 3-bromofurane 
• 67-72-1 hexachloroethane 

Downstream Products

• 743420-68-0 N-allylfuran-3-carboxamide 
• 58963-70-5 trans-3-furan-3-yl-acrylic acid ethyl ester 
• 80-07-9 4,4'-dichlorodiphenyl sulphone 
• 38980-69-7 3,4’-dichlorodiphenylsulfone 
• 14313-09-8 3-acetylfuran 

Relevant articles and documents

Decarboxylation method for heterocyclic carboxylic acid compounds

The invention relates to a decarboxylation method for heterocyclic carboxylic acid compounds. The method comprises the following steps: dissolving the heterocyclic carboxylic acid compounds in an aprotic polar solvent N,N-dimethylformamide, and performing decarboxylation at 85-150 DEG C with an organic acid as a catalyst. The method in the invention allows the yield of decarboxylation products obtained after a reaction to be higher than the yield of the products obtained through decarboxylation methods in the prior art, and does not need an expensive metal catalyst; and the solvent (DMF) in the present invention is more stable than DMSO, is not prone to decompose at a high temperature, and it can be recycled, so the cost is reduced. The method has the advantages of simple operation process, zero pollution, greenness, environmental protection and excellent application prospect.

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.