50690-53-4

Usage

Uses

Used in Pharmaceutical Industry:
(4-Isopropoxyphenyl)acetonitrile is used as an intermediate in the synthesis of pharmaceuticals for its ability to participate in organic reactions that lead to the creation of complex molecules with medicinal purposes.
Used in Agrochemical Industry:
(4-IsoPROPOXYPHENYL)ACETONITRILE is used as an intermediate in the synthesis of agrochemicals for its capacity to engage in organic reactions that result in the formation of complex molecules with agricultural applications.

Upstream product

• 14191-95-8 4-cyanomethylphenol 
• 75-26-3 isopropyl bromide 

Downstream Products

• 23528-51-0 1-Cyano-1-(4-isopropoxyphenyl)-cyclopentan 
• 74205-08-6 1-(4-Isopropoxy-phenyl)-cyclopropanecarbonitrile 
• 74205-22-4 1-(4-Isopropoxy-phenyl)-cyclobutanecarbonitrile 
• 89790-01-2 2-(4-Isopropoxy-phenyl)-acetamide 
• 924907-76-6 2-(4-isopropoxy-phenyl)-3-(4-methoxy-phenyl)-3-oxo-propionitrile 
• 61492-14-6 (2S,5R,6R)-6-{[1-(4-Isopropoxy-phenyl)-cyclopentanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 61492-46-4 (2S,5R,6R)-6-{[1-(4-Isopropoxy-phenyl)-cyclobutanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 61492-30-6 (2S,5R,6R)-6-{[1-(4-Isopropoxy-phenyl)-cyclopropanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 74316-96-4 1-(4-Isopropoxy-phenyl)-cyclopentanecarboxylic acid 
• 74205-49-5 1-(4-Isopropoxy-phenyl)-cyclobutanecarboxylic acid 
• 74205-36-0 1-(4-Isopropoxy-phenyl)-cyclopropanecarboxylic acid 
• 121060-09-1 Acetic acid (2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[3-(4-isopropoxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-tetrahydro-pyran-3-yl ester 
• 121060-04-6 Acetic acid (2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-{3-hydroxy-4-[2-(4-isopropoxy-phenyl)-acetyl]-phenoxy}-tetrahydro-pyran-3-yl ester 
• 924907-84-6 2-(4-methoxyphenyl)-3-(4-(2-piperidin-1-yl-ethoxy)-phenyl)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine 

Relevant academic research and scientific papers

Synthesis of lamellarin alkaloids using orthoester-masked α-keto acids

Pyruvic acid and other α-keto acids are frequently encountered as intermediates in metabolic pathways, yet their application in total synthesis has met with limited success. In this work, we present a bioinspired strategy that utilizes highly functionaliz

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains

2,3-Diarylpyrazolo[1,5-α]pyrimidines are estrogen receptor (ER) antagonists of modest potency that we have described previously. Guided by the crystal structure of an ER-ligand complex that we have obtained with one of these compounds, we prepared analogs that contain a basic side chain at the 2- or 3-aryl group and quickly found one that, according to the structure-based prediction, shows an increase in binding affinity and antagonist potency and a loss of residual agonist activity.

Design of Inhibitors from the Three-Dimensional Structure of Alcohol Dehydrogenase. Chemical Synthesis and Enzymatic Properties

Inhibitors of liver alcohol dehydrogenase were designed from the three-dimensional structure of the enzyme.The ligand to the catalytic zinc ion is an amide group or, better, a formamide group.With the latter function, a hydrogen bond between the NH group and the hydroxyl group of Ser-48 may be formed.The hydrophobic substrate binding site brings structural restraints. α-ω bifunctional molecules show good inhibitory properties possibly due to the interactions with polar residues at the entrance of the substrate binding site.