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3,5,6,7,8-Pentamethoxy-3',4'-methylenedioxyflavone is a complex organic compound belonging to the flavonoid class, characterized by its unique structure and properties. This molecule features a flavone backbone with five methoxy groups attached at positions 3, 5, 6, 7, and 8, and a methylenedioxy bridge connecting positions 3' and 4' on the flavone's B-ring. The presence of these functional groups imparts specific chemical and biological properties to the compound, making it a subject of interest in various fields, including pharmaceuticals, natural product chemistry, and materials science. Its potential applications may range from antioxidant and anti-inflammatory activities to the development of new drugs and bioactive compounds.

5071-42-1

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5071-42-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5071-42-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,7 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5071-42:
(6*5)+(5*0)+(4*7)+(3*1)+(2*4)+(1*2)=71
71 % 10 = 1
So 5071-42-1 is a valid CAS Registry Number.

5071-42-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name melibentin

1.2 Other means of identification

Product number -
Other names 3,5,6,7,8-pentamethoxy-3',4'-methylenedioxy-flavone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5071-42-1 SDS

5071-42-1Downstream Products

5071-42-1Relevant academic research and scientific papers

Synthesis of Polymethoxyflavonoids from Hesperidin and Naringin and their Antiproliferative Activity

Jin, Zhizhong,Liu, Kexiong,Su, Liang,Wang, Qiuan

, (2022/03/27)

[Figure not available: see fulltext.] A series of polymethoxyflavonoids were synthesized via cleavage of the glycosidic bond, dehydrogenation, selective methylation, bromination, nucleophilic aromatic substitution, O-prenylation, Claisen–Schmidt aldol condensation, cyclization, and oxidation from very abundant and inexpensive natural flavonoids hesperidin and naringin. The in vitro antiproliferative activity of the synthesized compounds was evaluated against a panel of four human cancer cell lines (Aspc-1, HCT-116, HepG-2, and SUN-5) by the CellTiter-Glo assay. The results showed that some of synthesized compounds exhibited moderate to high antiproliferative activity. Among them, (2E)-1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-3-(7-methoxy-1,3-benzodioxol-5-yl)prop-2-en-1-one was revealed to be the most active with IC50 values ranging from 10.35 to 13.89 μM against all four cancer cell lines, the IC50 value (10.35 μM) being below positive control cisplatin (12.36 μM) against HepG-2 cells.

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