50712-67-9

Basic information

• Product Name: 2-(bromomethyl)-4-chlorobenzonitrile
• Synonyms: 2-(bromomethyl)-4-chlorobenzonitrile
• CAS NO: 50712-67-9
• Molecular Formula: C₈H₅BrClN
• Molecular Weight: 230.489
• Mol File: 50712-67-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(bromomethyl)-4-chlorobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(bromomethyl)-4-chlorobenzonitrile(50712-67-9)
• EPA Substance Registry System: 2-(bromomethyl)-4-chlorobenzonitrile(50712-67-9)

Safety Data

• Hazardous Substances Data: 50712-67-9(Hazardous Substances Data)

Usage

General Description

2-(bromomethyl)-4-chlorobenzonitrile is a chemical compound consisting of a benzene ring with a cyano group (CN) and chlorine (Cl) attached at the 4th position, while a bromomethyl group is attached at the 2nd position. It is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of dyes and other organic compounds. The bromomethyl group makes the compound reactive towards nucleophiles, making it useful in various chemical reactions and processes. However, it is important to handle this chemical with caution, as it is toxic and may cause skin and eye irritation, as well as other health hazards if not properly handled.

Upstream product

• 50712-68-0 4-chloro-2-methylbenzonitrile 
• 34241-39-9 azobisisobutyronitrile 

Downstream Products

• 76519-94-3 2,3-bis(2-cyano-5-chlorophenyl)propionitrile 
• 1009633-62-8 C₂₂H₃₂ClN₃O₂ 
• 1009633-77-5 C₂₂H₃₂ClN₃O₂ 
• 1009633-59-3 C₂₂H₃₂ClN₃O₂ 
• 1009633-60-6 C₂₁H₃₀ClN₃O₂ 
• 1009633-64-0 C₂₂H₃₀ClN₃O₂ 
• 1009633-66-2 C₂₃H₃₂ClN₃O₂ 
• 1027346-03-7 C₁₉H₂₆ClN₃O₂ 
• 1027344-63-3 C₂₂H₃₂ClN₃O₂ 
• 1027346-09-3 C₁₈H₂₄ClN₃O₂ 
• 1027346-16-2 C₂₀H₂₈ClN₃O₂ 
• 1009633-79-7 C₂₂H₃₂ClN₃O₂ 
• 1009633-67-3 C₂₄H₂₈ClN₃O₂ 
• 1009633-52-6 C₁₉H₂₆ClN₃O₂ 

Relevant articles and documents

Palladium-Catalyzed Tandem Carbonylative Diels-Alder Reaction for Construction of Bridged Polycyclic Skeletons

A palladium-catalyzed tandem carbonylative lactonization and Diels-Alder cycloaddition reaction between aldehyde-tethered benzylhalides and alkenes has been developed. A range of alkenes and aldehyde-tethered benzylhalides bearing different substituents can be successfully transformed into the corresponding bridged polycyclic compounds in good yields. This strategy provides a unique approach to complex lactone-containing bridged polycyclic compounds.

PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS

In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.

Efficient one-step synthesis of chiral bidentate oxazoline-alcohol ligands via a cyclic imidate ester rearrangement

Various chiral bidentate oxazoline-alcohol ligands were obtained in a straightforward one-step synthesis via a cyclic imidate ester rearrangement. These chiral ligands were tested and compared in asymmetric diethylzinc additions to aldehydes resulting in