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2-(bromomethyl)-4-chlorobenzonitrile is a chemical compound that features a benzene ring with a cyano group (CN) and a chlorine (Cl) atom at the 4th position, and a bromomethyl group at the 2nd position. 2-(bromomethyl)-4-chlorobenzonitrile is known for its reactivity due to the bromomethyl group, which makes it a valuable intermediate in various chemical syntheses.

50712-67-9

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50712-67-9 Usage

Uses

Used in Pharmaceutical Industry:
2-(bromomethyl)-4-chlorobenzonitrile is used as a synthetic intermediate for the production of various pharmaceuticals. Its reactivity with nucleophiles allows for the creation of a wide range of drug molecules, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(bromomethyl)-4-chlorobenzonitrile serves as a key intermediate in the synthesis of agrochemicals. Its role in creating specific chemical structures is essential for the development of effective pesticides and other agricultural products.
Used in Dye Production:
2-(bromomethyl)-4-chlorobenzonitrile is used as a chemical intermediate in the production of dyes. 2-(bromomethyl)-4-chlorobenzonitrile's structure lends itself to the creation of diverse dye molecules, which are crucial for the textile and other industries that rely on colorants.
Used in Organic Compound Synthesis:
Beyond its applications in pharmaceuticals, agrochemicals, and dyes, 2-(bromomethyl)-4-chlorobenzonitrile is also used in the synthesis of other organic compounds. Its versatility in chemical reactions makes it a valuable component in the creation of a broad spectrum of organic molecules for various applications.
Safety Note:
It is important to handle 2-(bromomethyl)-4-chlorobenzonitrile with care due to its toxicity. It can cause skin and eye irritation and poses other health hazards if not properly managed. Proper safety measures and personal protective equipment are essential when working with 2-(bromomethyl)-4-chlorobenzonitrile.

Check Digit Verification of cas no

The CAS Registry Mumber 50712-67-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,7,1 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 50712-67:
(7*5)+(6*0)+(5*7)+(4*1)+(3*2)+(2*6)+(1*7)=99
99 % 10 = 9
So 50712-67-9 is a valid CAS Registry Number.

50712-67-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-benzamido-3-(3-methoxyphenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50712-67-9 SDS

50712-67-9Relevant articles and documents

Palladium-Catalyzed Tandem Carbonylative Diels-Alder Reaction for Construction of Bridged Polycyclic Skeletons

Wang, Siyuan,Zhou, Yangkun,Huang, Hanmin

supporting information, p. 2125 - 2129 (2021/04/05)

A palladium-catalyzed tandem carbonylative lactonization and Diels-Alder cycloaddition reaction between aldehyde-tethered benzylhalides and alkenes has been developed. A range of alkenes and aldehyde-tethered benzylhalides bearing different substituents can be successfully transformed into the corresponding bridged polycyclic compounds in good yields. This strategy provides a unique approach to complex lactone-containing bridged polycyclic compounds.

Annulation of o-Quinodimethanes through N-Heterocyclic Carbene Catalysis for the Synthesis of 1-Isochromanones

Janssen-Müller, Daniel,Singha, Santanu,Olyschl?ger, Theresa,Daniliuc, Constantin G.,Glorius, Frank

supporting information, p. 4444 - 4447 (2016/09/09)

The activation of 2-(bromomethyl)benzaldehydes using N-heterocyclic carbenes represents a novel approach to the generation of o-quinodimethane (o-QDM) intermediates. Coupling with ketones such as phenylglyoxylates, isatins, or trifluoromethyl ketones via [4 + 2] annulation gives access to functionalized 1-isochromanones.

PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS

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Paragraph 0843; 0844, (2015/11/25)

In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.

CYCLIC IMIDATE LIGANDS

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Page/Page column 7, (2012/04/05)

The present invention relates to a use of a cyclic imidate as a ligand for catalysis in which the ligand contains sub-structure (Y) as a minimal structural motive, wherein the carbon atoms and the nitrogen atom can be optionally substituted by a chemical substituent.

Efficient one-step synthesis of chiral bidentate oxazoline-alcohol ligands via a cyclic imidate ester rearrangement

Noel, Timothy,Robeyns, Koen,Meervelt, Luc Van,Eycken, Erik Van der,Eycken, Johan Van der

experimental part, p. 1962 - 1968 (2010/03/03)

Various chiral bidentate oxazoline-alcohol ligands were obtained in a straightforward one-step synthesis via a cyclic imidate ester rearrangement. These chiral ligands were tested and compared in asymmetric diethylzinc additions to aldehydes resulting in

Discovery of a series of aminopiperidines as novel iNOS inhibitors

Bourdonnec, Bertrand Le,Leister, Lara K.,Ajello, Christopher A.,Cassel, Joel A.,Seida, Pamela R.,O'Hare, Heather,Gu, Minghua,Chu, Guo-Hua,Tuthill, Paul A.,DeHaven, Robert N.,Dolle, Roland E.

, p. 336 - 343 (2008/09/18)

Nitric oxide (NO), a mediator of various physiological and pathophysiological processes, is synthesized by three isozymes of nitric oxide synthase (NOS). Potential candidate clinical drugs should be devoid of inhibitory activity against endothelial NOS (eNOS), since eNOS plays an important role in maintaining normal blood pressure and flow. A new series of aminopiperidines as potent inhibitors of iNOS were identified from a HTS lead. From this study, we identified compound 33 as a potent iNOS inhibitor, with >25-fold selectivity over eNOS and 16-fold selectivity over nNOS.

CYCLIC AMIDINES USEFUL AS NMDA NR2B ANTAGONISTS

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, (2008/06/13)

The invention encompasses novel compounds of Formula I as well as a method of treating NMDA mediated diseases comprising administration to a patient in need of such treatment a non-toxic amount of a compound of Formula I effective to block the NMDA NR2B r

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