50712-78-2

Basic information

• Product Name: Azetidine-2-carboxylicacidaMide
• CAS NO: 50712-78-2
• Molecular Formula: C4H8N2O
• Molecular Weight: 100.11912
• Mol File: 50712-78-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Azetidine-2-carboxylicacidaMide(CAS DataBase Reference)
• NIST Chemistry Reference: Azetidine-2-carboxylicacidaMide(50712-78-2)
• EPA Substance Registry System: Azetidine-2-carboxylicacidaMide(50712-78-2)

Safety Data

• Hazardous Substances Data: 50712-78-2(Hazardous Substances Data)

Usage

General Description

Azetidine-2-carboxylic acid, also known as Aze, is a cyclic amino acid that is not commonly found in natural proteins but has been identified in some bacteria. Its primary function is as a biosynthetic precursor for the amino acid proline. Aze is also known to exhibit nootropic and neuroprotective properties, potentially enhancing cognitive function and protecting against neurological damage. It has been investigated for its potential therapeutic applications in treating conditions such as Alzheimer's disease and schizophrenia. Additionally, Aze has been studied for its potential use in the development of new drugs and pharmaceutical compounds due to its unique chemical structure and biological activities.

Upstream product

• 205443-26-1 (S)-(-)-1-benzylazetidine-2-carboxamide 
• 1219220-82-2 tert-butyl 2-carbamoylazetidine-1-carboxylate 

Relevant articles and documents

2-Carboxamide Cycloamino Ureas

The present invention relates to compounds of formula I and salts thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol

COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV

The invention aims to provide a dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. The invention is directed to a compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or -COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1 and R2, together with a carbon atom to which they are bound, represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4 represents a hydrogen or a cyano group, D represents -CONR6-, -CO- or -NR6CO-, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents -(CH2)m- whereupon m is an integer of 1 to 3, -CH2OCH2-, or -SCH2-, n is an integer of 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.