50727-07-6

Basic information

• Product Name: 5-tert-butylisoindoline-1,3-dione
• Synonyms: 5-tert-butylisoindoline-1,3-dione
• CAS NO: 50727-07-6
• Molecular Formula: C₁₂H₁₃NO₂
• Molecular Weight: 203.23712
• Mol File: 50727-07-6.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-tert-butylisoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-tert-butylisoindoline-1,3-dione(50727-07-6)
• EPA Substance Registry System: 5-tert-butylisoindoline-1,3-dione(50727-07-6)

Safety Data

• Hazardous Substances Data: 50727-07-6(Hazardous Substances Data)

Usage

General Description

5-tert-butylisoindoline-1,3-dione is a chemical compound with the molecular formula C13H15NO2. It is a derivative of isoindoline-1,3-dione and contains a tert-butyl group in its structure. 5-tert-butylisoindoline-1,3-dione is used in organic synthesis and pharmaceutical research as a building block for various functional molecules. It has a wide range of applications in the production of dyes, pigments, and pharmaceuticals. 5-tert-butylisoindoline-1,3-dione has potential as a versatile intermediate in the synthesis of biologically active compounds and is also being researched for its potential pharmacological properties. Additionally, it may have use in the development of new materials and chemical processes.

Upstream product

• 84379-72-6 1,3-dioxoisoindolin-2-yl 3,3-dimethylbutanoate 
• 108139-26-0 (3-phenylpropylidene)propanedinitrile 
• 32703-80-3 4-(t-butyl)phthalonitrile 
• 95-47-6 o-xylene 
• 7397-06-0 4-t-butyl-o-xylene 
• 136918-14-4 phthalimide 
• 558-17-8 tert-Butyl iodide 
• 507-19-7 t-butyl bromide 
• 89379-02-2 tert-butylmercury iodide 
• 38442-51-2 tert-butylmercury chloride 
• 14236-13-6 4-(tert-butyl)phthalic acid 
• 52319-96-7 4-tert-Butylphthalsaeurediamid 
• 32703-79-0 4-tert-butylphthalic anhydride 

Downstream Products

• 1356116-19-2 methyl 4-tert-butyl-2-((methoxycarbonyl)amino)benzoate 
• 1356116-23-8 methyl 5-tert-butyl-2-((methoxycarbonyl)amino)benzoate 
• 717879-44-2 methyl 2-amino-4-tert-butylbenzoate 
• 52319-96-7 4-tert-Butylphthalsaeurediamid 

Relevant articles and documents

Direct Cyclopropanation of α-Cyano β-Aryl Alkanes by Light-Mediated Single Electron Transfer Between Donor–Acceptor Pairs

Cyclopropanes are traditionally prepared by the formal [2+1] addition of carbene or radical based C1 units to alkenes. In contrast, the one-pot intermolecular cyclopropanation of alkanes by redox active C1 units has remained unrealised. Herein, we achieve

Transition metal-free 1,3-dimethylimidazolium hydrogen carbonate catalyzed hydration of organonitriles to amides

An efficient hydration of organonitriles to the corresponding amides was accomplished using 1,3-dimethylimidazolium hydrogen carbonate as an organocatalyst. The developed catalytic method was also applicable for the synthesis of metal phthalocyanines.

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors

To obtain selective and potent inhibitors of dipeptidyl peptidases 8 and 9, we synthesized a series of substituted isoindolines as modified analogs of allo-Ile-isoindoline, the reference DPP8/9 inhibitor. The influence of phenyl substituents and different P2 residues on the inhibitors' affinity toward other DPPs and more specifically, their potential to discriminate between DPP8 and DPP9 will be discussed. Within this series compound 8j was shown to be a potent and selective inhibitor of DPP8/9 with low activity toward DPP II.