507276-76-8

Upstream product

• 186581-53-3 diazomethane 
• 47375-34-8 Boc-Tyr(t-Bu)-OH 
• 543-27-1 isobutyl chloroformate 

Downstream Products

• 1346226-85-4 C₂₂H₃₃NO₅ 
• 74974-40-6 (S)-trans-5-t-butoxycarbonylamino-6-(4-t-butoxyphenyl)hex-3-enoic acid 
• 1346227-01-7 C₂₂H₃₃NO₅ 
• 1346226-99-0 C₂₃H₃₅NO₅ 
• 1346226-88-7 C₂₂H₃₃NO₅ 
• 1346226-96-7 C₂₃H₃₅NO₅ 
• 1346226-93-4 C₂₁H₃₃NO₅ 
• 507277-19-2 2-benzyl-8-tert-butoxycarbonylamino-9-(4-tert-butoxy-phenyl)-3,6-dihydroxy-non-4-enethioic acid S-benzyl ester 
• 507276-79-1 [1-(4-tert-butoxy-benzyl)-3-hydroxy-pent-4-enyl]-carbamic acid tert-butyl ester 
• 507276-84-8 [1-(4-tert-butoxy-benzyl)-3-hydroxy-pent-4-enyl]-carbamic acid tert-butyl ester 
• 565430-84-4 [1-(4-tert-butoxybenzyl)-3-oxo-propyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Kinetic deconjugation: A gateway to the synthesis of Xxx-Gly (E)-alkene dipeptide isosteres

A new method for the preparation of Xxx-Gly (E)-alkene dipeptide isosteres (EADIs), using LDA deprotonation followed by 1 N HCl quench, was explored. The method, named kinetic deconjugation, enabled the synthesis of Tyr-Gly, Gly-Gly, Ser-Gly, Pro-Gly, and

MU OPIOID RECEPTOR LIGANDS: METHODS OF USE AND SYNTHESIS

Peptidomimetic compounds derived from aralkyl substitued 8-amino-3,7- or 3,6-dihydroxy alkenoic or alkanoic acids and compositions including those compounds, as well as methods of using and making the compounds are herein described. The compounds are usef

Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols.

Using olefin cross-metathesis, we synthesized a novel stereodiversified library of compounds 3 containing a trans-1,4-enediol. Screening this library for mu opioid receptor (MOR) affinity identified multiple high-affinity ligands and revealed that the ste