50735-12-1 Usage
Description
5-Chloro-3-ethylbenzo[c]isoxazole, also known as Clonitazene, is a synthetic opioid analgesic drug belonging to the benzimidazole class. It is characterized by its potent pain-relieving properties and unique chemical structure, which includes a chloro and ethyl substitution on the benzene ring, as well as an isoxazole ring. Clonitazene acts on the body's opioid receptors, similar to other opioids, and has been used for its analgesic and antitussive properties. However, due to its high potency and potential for abuse and dependence, it is classified as a Schedule I controlled substance in the United States.
Uses
Used in Pharmaceutical Industry:
5-Chloro-3-ethylbenzo[c]isoxazole is used as an analgesic agent for its potent pain-relieving properties. It is particularly effective in managing severe pain and has been utilized in various pharmaceutical formulations to provide relief to patients suffering from acute and chronic pain conditions.
Used in Antitussive Applications:
5-Chloro-3-ethylbenzo[c]isoxazole is used as an antitussive agent to suppress cough reflexes. Its effectiveness in reducing coughing makes it a valuable component in medications designed to alleviate symptoms associated with respiratory conditions, such as colds, bronchitis, and other respiratory infections.
Used in Opioid Dependence and Withdrawal Treatment:
5-Chloro-3-ethylbenzo[c]isoxazole has shown potential for use in the treatment of opioid dependence and withdrawal. Its interaction with the body's opioid receptors makes it a candidate for managing the symptoms and discomfort associated with opioid withdrawal, providing an alternative to other more addictive substances.
Check Digit Verification of cas no
The CAS Registry Mumber 50735-12-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,7,3 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 50735-12:
(7*5)+(6*0)+(5*7)+(4*3)+(3*5)+(2*1)+(1*2)=101
101 % 10 = 1
So 50735-12-1 is a valid CAS Registry Number.
50735-12-1Relevant articles and documents
Base-Mediated [3 + 4]-Cycloaddition of Anthranils with Azaoxyallyl Cations: A New Approach to Multisubstituted Benzodiazepines
Feng, Juan,Zhou, Meng,Lin, Xuanzi,Lu, An,Zhang, Xiaoyi,Zhao, Ming
supporting information, p. 6245 - 6248 (2019/09/06)
A new [3 + 4] cycloaddition of azaoxyallyl cations and anthranils has been achieved for rapid access to multisubstituted benzodiazepine derivatives. A variety of anthranils and α-halo hydroxamates were both effective substrates with simple operations unde
