10292-65-6

Basic information

• Product Name: 1-Cyclopropyl-2-nitrobenzene
• Synonyms: 1-Cyclopropyl-2-nitrobenzene
• CAS NO: 10292-65-6
• Molecular Formula: C₉H₉NO₂
• Molecular Weight: 163.18
• Product Categories: nitro-compound
• Mol File: 10292-65-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Cyclopropyl-2-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclopropyl-2-nitrobenzene(10292-65-6)
• EPA Substance Registry System: 1-Cyclopropyl-2-nitrobenzene(10292-65-6)

Safety Data

• Hazardous Substances Data: 10292-65-6(Hazardous Substances Data)

Usage

General Description

1-Cyclopropyl-2-nitrobenzene is a chemical compound with the molecular formula C9H9NO2. It is a substituted nitrobenzene with a cyclopropyl group attached to the benzene ring. 1-Cyclopropyl-2-nitrobenzene is commonly used in organic synthesis and as a building block for the preparation of various pharmaceuticals and agrochemicals. It is also known for its potential application as a photoactive material in the field of optoelectronics. Additionally, 1-Cyclopropyl-2-nitrobenzene is known to have some toxicity and should be handled with caution in laboratory settings.

Upstream product

• 598-58-3 methyl nitrate 
• 873-49-4 cyclopropylbenzene 
• 3158-73-4 2-cyclopropylaniline 
• 39773-68-7 4-Ethyl-2-nitrophenylcyclopropan 
• 57807-29-1 1-cyclopropyl-2-iodobenzene 
• 577-19-5 2-nitrophenyl bromide 
• 411235-57-9 cyclopropylboronic acid 

Downstream Products

• 3158-73-4 2-cyclopropylaniline 
• 30546-31-7 2,6-Dinitrophenylcyclopropan 
• 30546-30-6 2,4-dinitrophenylcyclopropane 
• 71759-37-0 Diethyl-N-(o-cyclopropylphenyl)phosphoramid 
• 92962-39-5 benzoic acid-(2-cyclopropyl-anilide) 
• 19936-12-0 4-bromo-2-cyclopropylacetanilide 
• 210297-34-0 2-acetamidophenylcyclopropane 
• 136605-78-2 1-(2-cyclopropylphenyl)piperazine 
• 74386-30-4 2-propionyl-2'-(1-hydroxypropyl)azobenzene 
• 74386-31-5 2-methyl-1-(2-propionylphenylamino)indole 
• 30546-32-8 2-Nitro-6-nitrosopropiophenon 
• 30546-33-9 1-(4-nitro-2-nitroso-phenyl)-propan-1-one 
• 1466-88-2 2-nitrocinnamic aldehyde 

Relevant articles and documents

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NITRATION

The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromatic ring comprises at least one heteroatom selected from the group consisting of oxygen, sulfur, phosphor, selenium and nitrogen, with a compound of formula (I) wherein Y is selected from the group consisting of hydrogen and nitro.

SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS

The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP1 receptor as well as to pharmaceutical compositions comprising them.

Radical ion probes. Part 10. Ceric(IV) ammonium nitrate oxidation of cyclopropylarenes

The chemistry of radical cations generated via the oxidation of several cyclopropylarenes with ceric(IV) ammonium nitrate in CH3CN-CH3OH is reported. For cyclopropylbenzene, the major product is 1-phenylpropane-1,3-diyl dinitrate, arising from ring opening of the cyclopropylbenzene radical cation. Experiments with 1-cyclopropyl-4-methylbenzene reveal that ring opening of cyclopropylbenzenes occurs substantially faster than side chain deprotonation. Cyclopropane ring opened products are also formed in the oxidation of 1- and 2-cyclopropylnaphthalenes. For 9-cyclopropylanthracene however, ring opened products are not detected. Instead, all products arising from this reaction are attributable to reaction of nucleophiles with the aromatic ring. Overall, these results confirm and extend earlier observations pertaining to the chemistry of cyclopropylarene radical cations. General principles associated with the use of cyclopropyl groups as "probes" for radical cation intermediates, and general principles governing radical ion ring openings are discussed.