50744-87-1Relevant academic research and scientific papers
A new cationic gemini surfmer: Synthesis and surface activities
Su, Xin,Wang, Biqing,Lu, Zhiyong,Wei, Limin,Feng, Yujun
, p. 73 - 76 (2011)
A new cationic gemini surfmer (polymerizable surfactant or surface-active monomer) with an acrylic reactive group in its spacer group was synthesized and characterized, and its surface activity properties were examined in comparison with its intermediate surfactant 12-3OH-12?2Cl-, a previously-reported gemini surfmer 12′-2-12′?2Br-, as well as monomeric surfactant dodecyl trimethylammonium bromide. It was found that neither the incorporation of a double bond onto the gemini surfactant nor the change of location of the double bond will affect surface activities of the gemini surfactant.
Comparative screening of tetra-chlorometallate anions in novel magnetic metallogeminisurfactant catalysts for advanced synthesis of an anti-tumor benzothiazol-based aminophosphonate drug (ACBTAP)
Tamaddon, Fatemeh,Tadayonfar, SeydEhsan
, p. 51 - 57 (2019)
Due to the high surface activity and low critical micelle concentration (CMC) of metallogemini-surfactants (MGSs), in this work various magnetic MGSs (MMGS1s) were prepared by simple grinding of low-cost hydrated salts of Fe3+, Co2+, Mn2+ and Ni2+ with GS1 synthesized by an improved solvent-free method. These new MMGS1s, which are complexes of 2FeCl4 ?, CoCl4 2?, MnCl4 2?, and NiCl4 2? with GS1, were characterized by UV–Vis, FT-IR, and melting point (mp) analyses. So, the maximum UV–Vis absorption wavelength was due to the GS1 2+·CoCl4 2? and the minimum mp and pH were due to the GS1 2+ ·2FeCl4 ? (MFeGS1). The results of the catalytic activities of MMGS1s in solvent-free synthesis of anticancer O,O′-diethyl-α-(benzothiazole-2-yl)amino(phenylmethyl) phosphonate (ACBTAP) revealed the superiority of MFeGS1, although catalysts were isolated as aqueous magnetic liquids (MLs) by addition of water. The aqueous MLs were further prepared in 0.01 and 0.1 molar concentration and analyzed by pH, surface tension (?), superconducting quantum interface device magnetometer (SQUID), and magnetic tests. Similar to GS1, all MMGS1s reduced the ? of water by a half time ratio, while the magnetic activity of their aqueous MLs confirmed by magnetic drop-deviation and drop-movement over organic phase. The SQUID analysis of the aqueous MLs supported ferromagnetic properties for solution of MCoGS1, MNiGS1, and MMnGS1 in water and paramagnetic properties for the aqueous solution of GS1 2+·2FeCl4 ?. The as-prepared MLs are novel polar alternatives for organic solvents, water-treatment sorbents, and magnetic delivery of biomaterials.
Acrylic acid biquaternary ammonium salt monomer and preparation method thereof
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Paragraph 0033-0034, (2020/06/20)
The invention belongs to the technical field of biquaternary ammonium salt. The invention particularly relates to an acrylic acid biquaternary ammonium salt monomer and a preparation method thereof. The structural general formula of the acrylic acid biquaternary ammonium salt monomer is shown in Figure 3, and the preparation method of the acrylic acid biquaternary ammonium salt monomer comprises the following steps: (1) dissolving a raw material I and a raw material II in a first organic solvent, adding a catalyst, reacting at 60-90 DEG C for 24-72 hours, and purifying to obtain an intermediate product 1; wherein the molar ratio of the raw material I to the raw material II is 1.0: (2.0-3.6); and (2) dissolving the intermediate product 1 into a second organic solvent, adding a neutralizer and a raw material III, reacting at 0-50 DEG C for 6-36 hours, and purifying to obtain an acrylic acid biquaternary ammonium salt monomer;; wherein the molar ratio of the intermediate product 1 to theraw material III to the neutralizer is 1.0: (1.0-1.5): (1.0-1.5), and the acrylic acid biquaternary ammonium salt monomer has good surface activity and antibacterial property.
A novel bi-functional surfactant-based paramagnetic deep-eutectic catalyst for improved benzoin condensation and multi-component synthesis of pyrrole derivatives
Tamaddon, Fatemeh,Tadayonfar, SeydEhsan
, p. 71 - 78 (2019/02/19)
A new professional magnetic surfactant-based deep-eutectic (DE) and viscose liquefy catalyst (GS2+·2FeCl4, MGSFe) was synthesized by an optimized reaction of the as-prepared cationic gemini-surfactant (GS) with two moles of FeCl3·6H2O. The structure of the GS and MGSFe were characterized by NMR, FT-IR, UV–visible, CHN, pH, surface tension (?), and vibrating sample magnetometry (VSM) analyses. The MGSFe, that is a high viscose brownish liquid at >50 °C, was successfully tested as a highly active paramagnetic catalyst for improved benzoin condensation and three-component synthesis of substituted pyrroles with the highest turnover number (TON) and turnover frequency (TOF) that ever reported for this purpose. The superior activity of MGSFe is due to its amphiphile properties, the synergistic effects between GS2+ and 2FeCl4 ? as hydrogen-bond-donor and magnetic hydrogen-bond-acceptor components of this novel magneto-responsive DE, and reusability without loss of activity even in four consequence cycles run for synthesis of pyrroles. This magnetic GS-based DE can be used as oil miscible additive, pollutant adsorbent, and carrier of biomaterials to targeted poisons.
Oligomeric quaternary ammonium salt bactericide and preparation method thereof
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Paragraph 0030; 0031, (2017/10/07)
The invention relates to an oligomeric quaternary ammonium salt bactericide and a preparation method thereof. Ester p-toluenesulfonate-based gemini quaternary ammonium salt, guanidine hydrochloride and sodium alkoxide are added into solvent, stirred and heated to 120 DEG C to 180 DEG C, heating is stopped after 10 to 48 hours of reaction, so that a crude product is obtained, and after post-treatment, the oligomeric quaternary ammonium salt bactericide is obtained; and the substance amount ratio of the ester p-toluenesulfonate-based gemini quaternary ammonium salt, the guanidine hydrochloride and the sodium alkoxide is (0.008 to 0.040):0.008:0.008. The gemini quaternary ammonium salt is introduced to a plurality of active sites, eight active sites are contained in the structure of the oligomeric quaternary ammonium salt bactericide, the oligomeric quaternary ammonium salt bactericide can show good water solubility and surface activity in aqueous solution, and an important role is played in the process of oligomeric quaternary ammonium salt preparation. A bacteria killing test on three types of bacteria, i.e. sulfate reducing bacteria, iron bacteria and saprophytic bacteria, indicates that the oligomeric quaternary ammonium salt bactericide has a good bactericidal effect.
P-toluenesulfonate-group Gemini quaternary ammonium salt and preparation method thereof
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Paragraph 0042; 0043, (2016/10/17)
The invention relates to a p-toluenesulfonate-group Gemini quaternary ammonium salt and a preparation method thereof. The preparation method comprises the following steps: adding long-chain alkyl tertiary amine and isopropanol into a container, heating, and dropwisely adding hydrochloric acid; after the dropwise addition, stirring uniformly, dropwisely adding epoxy chloropropane into the container, and reacting to obtain the hydroxypropyl Gemini quaternary ammonium salt; and adding the hydroxypropyl Gemini quaternary ammonium salt and paratoluensulfonyl chloride into a solvent, stirring uniformly, dropwisely adding a NaOH solution while stirring until the reaction is completed, stopping stirring, and heating to obtain the p-toluenesulfonate-group Gemini quaternary ammonium salt. The p-toluenesulfonate-group Gemini quaternary ammonium salt simultaneously has two hydrophilic quaternary ammonium salt groups; and the plane structure of the p-toluenesulfonate-group benzene ring in the linking group, the lone electron pair of heteroatoms in the sulfonate group and the metal surface can easily form a coordinate bond, so that the molecules form a film on the iron pipe wall, thereby facilitating the corrosion inhibition effect on the steel pipeline. The sulfonate group can not be easily hydrolyzed and decomposed in water, and thus, can not further pollute the water body.
Chloridized didodecyl dimethyl hydroxypropyl biquaternary ammonium salt bactericide
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Paragraph 0027; 0030-0036, (2018/02/04)
The invention discloses a preparation method of chloridized didodecyl dimethyl hydroxypropyl biquaternary ammonium salt bactericide. The preparation technology comprises the following steps that 50 kilograms of dodecyl tertiary amine, 38 kilograms of ethyl alcohol and 71 kilograms of water are put into a vacuum reaction kettle, the temperature is increased to 50 DEG C while stirring is conducted, then 23 kilograms of epoxy chloropropane is added, an exothermic phenomenon is generated at the moment, the temperature of the raw materials contained in the reaction kettle is controlled at 50 DEG C, and then reacting under stirring is conducted for 3 hours; 50 kilograms of dodecyl tertiary amine, 17 kilograms of hydrochloric acid and 71 kilograms of water are added into the reaction kettle, the temperature of the raw materials contained in the kettle is controlled at 70 DEG C, and reacting under stirring is conducted for 3 hours; the PH value of mixed liquid contained in the reaction kettle is regulated to be 8+/-2 with hydrochloric acid, reacting under stirring is conducted for 0.5 hour, and then the chloridized didodecyl dimethyl hydroxypropyl biquaternary ammonium salt bactericide is prepared.
PHYSICAL ANTIMICROBIAL METHOD
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Paragraph 0076, (2015/06/17)
The present invention relates to a physical antimicrobial method, which has the action of combating or inhibiting microorganisms when applied to the surface of human or animal body or an object. The method is safe for human body, and can prevent drug resistance caused by an antibacterial drug.
PHYSICAL ANTIMICROBIAL METHOD
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Paragraph 0076, (2015/07/02)
The present invention relates to a physical antimicrobial method, which has the action of combating or inhibiting microorganisms when applied to the surface of human or animal body or an object. The method is safe for human body, and can prevent drug resistance caused by an antibacterial drug.
A convenient synthesis of quaternary ammonium gemini surfactants from long-chain alkyldimethylamines and epichlorohydrin
Ricci,Cabrera,Luna,Grau
, p. 1811 - 1814 (2007/10/03)
Aqueous micellar systems proved to be an excellent reaction medium for the selective synthesis of bis-quaternary ammonium salts 5a-c from epichlorohydrin 2 and long-chain alkyldimethylamines 1a-c, in the presence of the corresponding amine chlorohydrates
