507472-25-5 Usage
Description
FMOC-(S)-3-AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID, also known as (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic Acid, is a synthetic compound with a unique chemical structure that features a fluorenylmethoxycarbonyl (Fmoc) group and a nitrophenyl group. FMOC-(S)-3-AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID is characterized by its potential applications in various fields, particularly in analytical chemistry and peptide synthesis.
Uses
Used in Analytical Chemistry:
FMOC-(S)-3-AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID is used as an analytical reagent for assessing the skin sensitization potential of test substances. It plays a crucial role in identifying and quantifying the allergenic properties of chemicals, which is essential for ensuring the safety of consumer products and the environment.
Used in Peptide Synthesis:
In the field of peptide synthesis, FMOC-(S)-3-AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID serves as a valuable building block for the creation of complex peptide sequences. The Fmoc group in the compound allows for selective protection and deprotection of the amino group during the synthesis process, enabling the stepwise assembly of peptides with high precision and yield.
Used in Skin Sensitization Assays:
FMOC-(S)-3-AMINO-3-(2-NITRO-PHENYL)-PROPIONIC ACID is used as a resin-fixing peptide in skin sensitization assays. This application takes advantage of the compound's ability to covalently attach to solid support materials, such as resins, facilitating the immobilization of peptides for further analysis and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 507472-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,7,4,7 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 507472-25:
(8*5)+(7*0)+(6*7)+(5*4)+(4*7)+(3*2)+(2*2)+(1*5)=145
145 % 10 = 5
So 507472-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C24H20N2O6/c27-23(28)13-21(19-11-5-6-12-22(19)26(30)31)25-24(29)32-14-20-17-9-3-1-7-15(17)16-8-2-4-10-18(16)20/h1-12,20-21H,13-14H2,(H,25,29)(H,27,28)/t21-/m0/s1
507472-25-5Relevant articles and documents
Light-mediated liberation of enzymatic activity: Small molecule caged protein equivalents
Li, Haishan,Hah, Jung-Mi,Lawrence, David S.
supporting information; experimental part, p. 10474 - 10475 (2009/02/05)
Light-activatable ( caged ) proteins have been used to correlate, with exquisite temporal and spatial control, intracellular biochemical action with global cellular behavior. However, the chemical or genetic construction of caged proteins is nontrivial, with subsequent laborious introduction into living cells, potentially problematic competition with natural endogenous counterparts, and challenging intracellular incorporation at levels equivalent to the natural enzymes. We describe the design, synthesis, and characterization of small molecular equivalents of a caged Src kinase. These compounds are easy to prepare and function by inhibiting the action of the natural unmodified enzyme. Copyright
